Haemodynamics Support during Surgical Myocardial Revascularisation in Patients with Systolic Left Ventricular Dysfunction

N. V. Kharitonov, V. V. Vitsukaev, N. A. Trofimov, P. D. Makalsky, V. N. Zavgorodny
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Abstract

Coronary heart disease remains a leading cause of death worldwide, and coronary bypass surgery -- the treatment standard in haemodynamically significant multivessel and/or trunk coronary stenosis. Intraoperative haemodynamics support during coronary artery bypass grafting (CABG) in patients with reduced ejection fraction currently remains controversial. Manifold evidence favours CABG with no extracorporeal circulation in higher risk patients to avoid the system’s frequent complications of blood transfusion, renal failure, bleeding, wound infection, cerebrovascular events and humoral disturbances. On the other hand, CABG with extracorporeal circulation and heart arrest allows a bloodless operating field and complete revascularisation in most, often very complex, cases. The complication rate and outcome in beating-heart surgery are reckoned to depend directly on the relevant surgeon’s and clinic experience, which makes many relinquish the technique due to a limited history of skill. This essay overviews the current state of the art, discussions of recent systematic studies on intraoperative haemodynamics support in patients with reduced left ventricular ejection fraction and touches upon the importance of surgeon’s experience for the operation outcome.
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收缩期左心室功能不全患者手术心肌血运重建术中的血流动力学支持
冠心病仍然是世界范围内死亡的主要原因,冠状动脉搭桥手术是血液动力学显著的多血管和/或主干冠状动脉狭窄的治疗标准。射血分数降低患者冠状动脉旁路移植术(CABG)期间的术中血液动力学支持目前仍存在争议。多种证据支持高危患者在不进行体外循环的情况下进行冠状动脉旁路移植,以避免系统的频繁并发症,如输血、肾衰竭、出血、伤口感染、脑血管事件和体液紊乱。另一方面,体外循环和心脏骤停的冠状动脉旁路移植术允许在大多数情况下(通常是非常复杂的情况下)进行无血手术和完全血运重建。心脏跳动手术的并发症发生率和结果被认为直接取决于相关外科医生和临床经验,这使得许多人由于技术史有限而放弃了这项技术。本文综述了目前的技术现状,讨论了最近对左心室射血分数降低患者术中血液动力学支持的系统研究,并谈到了外科医生经验对手术结果的重要性。
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审稿时长
12 weeks
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