Prince Sharma, K. Sharma, Mandeep Singh, P. Chadha
{"title":"Environmental Fate, Exposure and Toxicity of New Emerging Pollutant: Tetrabromobisphenol A.","authors":"Prince Sharma, K. Sharma, Mandeep Singh, P. Chadha","doi":"10.18311/ti/2022/v29i1/27859","DOIUrl":null,"url":null,"abstract":"Brominated Flame Retardants (BFRs) are being utilized to reduce the flammability of plastics, textiles, and electronics. They differ in their chemical properties and structures, and it is conventional that these distinctions alter their biological interactions as well as toxicity. Tetra-Bromo-Bis-Phenol A (TBBPA) is a pervasive environmental contaminant that is seen in both abiotic and biotic matrices. This review discusses the occurrence, distribution, and fate of TBBPA from source to the environment. Recent studies have raised worry over the potentially harmful implications of TBBPA exposure in humans and wildlife, prompting its characterization under group 2A “Probably carcinogenic to humans” by the International Agency for Research on Cancer. Worldwide there are no present confinements on its production and usage. On the other hand, very little information is accessible with respect to its toxicity to humans and aquatic animals. More research is required to characterize human exposure to TBBPA in and around production facilities, as well as in e-waste recycling regions. So as to safeguard the environment and human health, detailed investigations are urgently needed, especially on tracking the exposure pathways which may affect the workers and local residents around the exposure sites.","PeriodicalId":23205,"journal":{"name":"Toxicology International","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicology International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18311/ti/2022/v29i1/27859","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 1
Abstract
Brominated Flame Retardants (BFRs) are being utilized to reduce the flammability of plastics, textiles, and electronics. They differ in their chemical properties and structures, and it is conventional that these distinctions alter their biological interactions as well as toxicity. Tetra-Bromo-Bis-Phenol A (TBBPA) is a pervasive environmental contaminant that is seen in both abiotic and biotic matrices. This review discusses the occurrence, distribution, and fate of TBBPA from source to the environment. Recent studies have raised worry over the potentially harmful implications of TBBPA exposure in humans and wildlife, prompting its characterization under group 2A “Probably carcinogenic to humans” by the International Agency for Research on Cancer. Worldwide there are no present confinements on its production and usage. On the other hand, very little information is accessible with respect to its toxicity to humans and aquatic animals. More research is required to characterize human exposure to TBBPA in and around production facilities, as well as in e-waste recycling regions. So as to safeguard the environment and human health, detailed investigations are urgently needed, especially on tracking the exposure pathways which may affect the workers and local residents around the exposure sites.
期刊介绍:
Toxicology International is a peer-reviewed International Research Journal published bi-annually by the Society of Toxicology, India. The Journal is concerned with various disciplines of Toxicology including man, animals, plants and environment and publishes research, review and general articles besides opinions, comments, news-highlights and letters to editor.