Study protocol for a national retrospective review of femoral periprosthetic fracture management. Is there variation in practice?

A. Nasser, Govind S Chauhan, Khabab Osman, Saroop Nandra, R. Nandra, A. Mahmood
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引用次数: 4

Abstract

The incidence of femoral periprosthetic fractures (PPFs) in the UK is on the rise. This rising incidence presents a clinical and an economic burden on the national health care services. There is also uncertainty about the most effective treatment modality for femoral PPFs, as well as a lack of evidence for a standardized management approach. We aimed to identify the true incidence and any variation in the management of femoral PPFs nationally. This multicentre national collaborative study has been designed by a trainee led research network in collaboration with a well-established university research organization. Data will be collected from participating centres over a period of 10 years (2010–2019). All adults presenting with a femoral PPF will be identified, and the mode of treatment for each fracture subtype will be recorded. Other measures will evaluate patient and treatment variables, objective and subjective outcome measures. Univariate and multivariate regression analyses will be used, as well as the coefficient of determination (R) in an attempt to measure the degree to which the models could explain the variation in management. This multicentre national project was approved by the local clinical governance department at each participating hospital site. The results of this study will be submitted to international peer reviewed journals and appropriate national and international conferences.
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股骨假体周围骨折处理的全国回顾性研究方案。在实践中有变化吗?
在英国,股骨假体周围骨折的发生率呈上升趋势。这种发病率的上升给国家医疗服务带来了临床和经济负担。股骨PPF最有效的治疗方式也存在不确定性,也缺乏标准化管理方法的证据。我们旨在确定全国范围内股骨PPF的真实发病率和管理中的任何变化。这项多中心的国家合作研究是由一个由实习生领导的研究网络与一个成熟的大学研究组织合作设计的。数据将从参与中心收集,为期10年(2010-2019年)。将确定所有出现股骨PPF的成年人,并记录每种骨折亚型的治疗模式。其他指标将评估患者和治疗变量、客观和主观结果指标。将使用单变量和多变量回归分析,以及决定系数(R),试图衡量模型对管理变化的解释程度。该多中心国家项目得到了各参与医院所在地当地临床治理部门的批准。这项研究的结果将提交给国际同行评审期刊以及适当的国家和国际会议。
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