Antihypertension Medication Usage Pattern and Predictors of Evidence-based Medication among Hypertension patients

IF 0.4 Q4 PHARMACOLOGY & PHARMACY Asian Journal of Pharmaceutics Pub Date : 2020-09-18 DOI:10.22377/AJP.V14I03.3760
M. Iqbal
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Abstract

Background: Despite substantial guidelines on the effective management of hypertension, many studies demonstrated an underutilization of evidence-based medicine (EBM) for the treatment of hypertension patients. This study aimed to evaluate the antihypertension therapy and the impact of patients’ specific predictors on the utilization of EBM among hypertension patients. Materials and Methods: A retrospective observational study designed to investigate the prescribing trends and patient’s factors (predictors) affecting the utilization of antihypertensive medications. Patients’ factors included age, gender, ethnicity, smoking status, and concurrent medical conditions. The study was conducted using a purpose-developed data collection form to assemble the patient’s information. Results: A total of 170 hypertensive patients, comprising 83 males (48.82%) and 87 females (51.18%) were selected as subjects for this study. The findings suggested that the mean age of our study population was 59.32 years and 70% of them had two to three comorbidities. It was established that 98.8% of the patients had chronic kidney disease and 35.3% of them were in Stage V. Diuretics were the most commonly prescribed antihypertensive class under monotherapy. Conclusion: This study evaluated antihypertension medications usage pattern and patients’ predictors affecting utilization of antihypertension medications among hypertension patients.
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高血压患者抗高血压药物使用模式及循证用药预测因素
背景:尽管有大量关于高血压有效管理的指导方针,但许多研究表明,循证医学(EBM)在高血压患者治疗中的利用不足。本研究旨在评估高血压患者的降压治疗以及患者的特定预测因素对EBM应用的影响。材料和方法:一项回顾性观察性研究,旨在调查处方趋势和影响降压药物使用的患者因素(预测因素)。患者的因素包括年龄、性别、种族、吸烟状况和并发疾病。该研究使用专门开发的数据收集表来收集患者的信息。结果:共有170名高血压患者被选为本研究的受试者,包括83名男性(48.82%)和87名女性(51.18%)。研究结果表明,我们研究人群的平均年龄为59.32岁,其中70%的人有两到三种合并症。据证实,98.8%的患者患有慢性肾脏疾病,其中35.3%处于V期。利尿药是单药治疗下最常见的降压药。结论:本研究评估了高血压患者抗高血压药物的使用模式和影响抗高血压药物使用的患者预测因素。
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来源期刊
Asian Journal of  Pharmaceutics
Asian Journal of Pharmaceutics PHARMACOLOGY & PHARMACY-
自引率
0.00%
发文量
47
期刊介绍: Character of the publications: -Pharmaceutics and Pharmaceutical Technology -Formulation Design and Development -Drug Discovery and Development Interface -Manufacturing Science and Engineering -Pharmacokinetics, Pharmacodynamics, and Drug Metabolism -Clinical Pharmacology, General Medicine and Translational Research -Physical Pharmacy and Biopharmaceutics -Novel Drug delivery system -Biotechnology & Microbiological evaluations -Regulatory Sciences
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