HYPOLIPIDEMIC AND HYPOGLYCEMIC ACTIVITY OF MEDICINAL PLANTS IN STZ (STREPTOZOTOCIN) INDUCED HYPERLIPIDEMIC RATS AND THEIR ROLE IN HEALTH AND DISEASE

Abstract

In the past few years, medical plants research focused on a lot by scientists all over the world. Many evidence has been studied to show the potential effects of medicinal plants in the medical field. This is due to the presence of many metabolites in plants that includes flavonoids, tannins, terpenoids, and many hypolipidemic and hypoglycemic agents. This study aims to evaluate various medicinal plants for anti-diabetic and hypolipidemic activity in rats. Diabetes mellitus is one of the most common non communicable diseases present globally and it’s most lethal complication which developed is dyslipidemia which ultimately leads to cardiovascular events which are hard to control and it’s not possible to revert back its effects. Since ancient times plants have been the source of medicine. Many kinds of literature mentioned the use of plants in the treatment of various diseases. This review covers the anti-diabetic and antihyperlipidemic effects of medicinal plants. Investigation of phytochemicals present in medicinal plants and their biological activities are reported. The hypolipidemic activity which is present in most medicinal plants is strongly associated with new drug development which will be used for high lipid profiles and cardiovascular disease.