Research progress in cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy for peritoneal metastasis of colorectal cancer

Abstract

Colorectal cancer peritoneal metastasis has traditionally been considered as one of the end-stage manifestations. Recently, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy achieved promising results in prolonging survival of patients and reducing tumor recurrences. Many guidelines suggested that the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy is an acceptable treatment for peritoneal metastasis. This article highlighted the treatment method, reviewed the latest evidence in treatment of colorectal cancer peritoneal metastasis and explored future direction. Key words: Colorectal neoplasms; Colorectal cancer; Peritoneal metastasis; Hyperthermic intraperitoneal chemotherapy; Cytoreductive surgery