{"title":"Clinical significance of large spontaneous portosystemic shunts in Budd-Chiari syndrome","authors":"X. Dang, Qingbo Meng, Luhao Li","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.010","DOIUrl":null,"url":null,"abstract":"Objective \nTo explore the clinical significance of large spontaneous portosystemic shunts ( L-SPSS ) in Budd-Chiari syndrome ( B-CS ). \n \n \nMethods \nClinical data of 382 B-CS patients treated at The First Affiliated Hospital of Zhengzhou University from Apr 2012 to Dec 2018 were analyzed retrospectively and we included 32 patients with B-CS complicated L-SPSS ( diameter>8 mm ). 65 patients without L-SPSS were selected randomly to form the control group. The correlation between L-SPSS and liver function, upper gastrointestinal bleeding, ascites, hepatic encephalopathy, inferior vena cava thrombosis , portal vein diameter and splenic vein diameter were analyzed. \n \n \nResults \nTBil, Child-Pugh scores, incidence of hepatic encephalopathy, ascites and inferior vena cava thrombosis in the B-CS complicated L-SPSS group were higher than that in the B-CS without L-SPSS group . The percentage of Child-Pugh grade B and C patients in the B-CS complicated L-SPSS group were also higher than that in the B-CS without L-SPSS group. The level of ALB and hepatic volume per unit surface area were both significantly less in the experimental group.( P 0.05 ) . \n \n \nConclusions \nFor those B-CS patients complicated L-SPSS , hepatic encephalopathy and ascites are more frequent, and they usually have poorer liver function. \n \n \nKey words: \nBudd-Chiari syndrome; Hypertension, portal; Collateral circulation","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华普通外科杂志","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To explore the clinical significance of large spontaneous portosystemic shunts ( L-SPSS ) in Budd-Chiari syndrome ( B-CS ).
Methods
Clinical data of 382 B-CS patients treated at The First Affiliated Hospital of Zhengzhou University from Apr 2012 to Dec 2018 were analyzed retrospectively and we included 32 patients with B-CS complicated L-SPSS ( diameter>8 mm ). 65 patients without L-SPSS were selected randomly to form the control group. The correlation between L-SPSS and liver function, upper gastrointestinal bleeding, ascites, hepatic encephalopathy, inferior vena cava thrombosis , portal vein diameter and splenic vein diameter were analyzed.
Results
TBil, Child-Pugh scores, incidence of hepatic encephalopathy, ascites and inferior vena cava thrombosis in the B-CS complicated L-SPSS group were higher than that in the B-CS without L-SPSS group . The percentage of Child-Pugh grade B and C patients in the B-CS complicated L-SPSS group were also higher than that in the B-CS without L-SPSS group. The level of ALB and hepatic volume per unit surface area were both significantly less in the experimental group.( P 0.05 ) .
Conclusions
For those B-CS patients complicated L-SPSS , hepatic encephalopathy and ascites are more frequent, and they usually have poorer liver function.
Key words:
Budd-Chiari syndrome; Hypertension, portal; Collateral circulation