Rapid synthesis of gold nanoparticles using silk fibroin: characterization, antibacterial activity, and anticancer properties

IF 2.2 4区 工程技术 Q2 Chemistry Gold Bulletin Pub Date : 2017-08-22 DOI:10.1007/s13404-017-0218-8
B. Lakshmeesha Rao, Mahadev Gowda, S. Asha, K. Byrappa, B. Narayana, R. Somashekar, Y. Wang, L. N. Madhu, Y. Sangappa
{"title":"Rapid synthesis of gold nanoparticles using silk fibroin: characterization, antibacterial activity, and anticancer properties","authors":"B. Lakshmeesha Rao,&nbsp;Mahadev Gowda,&nbsp;S. Asha,&nbsp;K. Byrappa,&nbsp;B. Narayana,&nbsp;R. Somashekar,&nbsp;Y. Wang,&nbsp;L. N. Madhu,&nbsp;Y. Sangappa","doi":"10.1007/s13404-017-0218-8","DOIUrl":null,"url":null,"abstract":"<p>In the present work, well-dispersed gold nanoparticles (AuNPs) were synthesised by the reduction of HAuCl<sub>4.</sub>xH<sub>2</sub>O using silk fibroin as a reducing agent. UV-visible spectroscopy confirmed the formation of AuNPs by showing surface plasmon resonance (SPR) at 526–518?nm. The FT-IR study revealed that the hydroxyl groups in the Tyr residue and the carboxyl groups in the Asp and/or Glu residues were the most active functional groups for the conversion of Au ion reduction. The transmission electron microscope (TEM) images showed that the formed nanoparticles were uniformly embedded in the silk fibroin solution. The AuNPs are spherical in shape with smooth edges and around 5–8?nm in diameter. Also, these possess very good stability and dispersity and can be stored for a long period. Further, the X-ray diffraction (XRD) study confirmed the nanocrystalline phase of the gold with cubic crystal structure. The biogenic gold nanoparticles displayed antibacterial activity against Gram-positive and Gram-negative bacteria, and also showed promising anticancer properties.</p>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2017-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13404-017-0218-8","citationCount":"31","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gold Bulletin","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s13404-017-0218-8","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Chemistry","Score":null,"Total":0}
引用次数: 31

Abstract

In the present work, well-dispersed gold nanoparticles (AuNPs) were synthesised by the reduction of HAuCl4.xH2O using silk fibroin as a reducing agent. UV-visible spectroscopy confirmed the formation of AuNPs by showing surface plasmon resonance (SPR) at 526–518?nm. The FT-IR study revealed that the hydroxyl groups in the Tyr residue and the carboxyl groups in the Asp and/or Glu residues were the most active functional groups for the conversion of Au ion reduction. The transmission electron microscope (TEM) images showed that the formed nanoparticles were uniformly embedded in the silk fibroin solution. The AuNPs are spherical in shape with smooth edges and around 5–8?nm in diameter. Also, these possess very good stability and dispersity and can be stored for a long period. Further, the X-ray diffraction (XRD) study confirmed the nanocrystalline phase of the gold with cubic crystal structure. The biogenic gold nanoparticles displayed antibacterial activity against Gram-positive and Gram-negative bacteria, and also showed promising anticancer properties.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
利用丝素蛋白快速合成金纳米粒子:表征、抗菌活性和抗癌特性
在本工作中,通过还原HAuCl4合成了分散良好的金纳米颗粒(AuNPs)。以丝素蛋白为还原剂的xH2O。紫外可见光谱在526 ~ 518 nm处显示表面等离子体共振(SPR),证实了AuNPs的形成。FT-IR研究表明,Tyr残基中的羟基和Asp和/或Glu残基中的羧基是Au离子还原转化最活跃的官能团。透射电子显微镜(TEM)图像显示,形成的纳米颗粒均匀地嵌入丝素溶液中。aunp的形状是球形的,边缘光滑,大约在5-8 ?直径为Nm。具有很好的稳定性和分散性,可以长期保存。x射线衍射(XRD)研究证实了金的纳米晶相具有立方晶体结构。生物源金纳米颗粒对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性,并显示出良好的抗癌性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Gold Bulletin
Gold Bulletin 工程技术-材料科学:综合
CiteScore
3.30
自引率
4.50%
发文量
0
审稿时长
3 months
期刊介绍: Gold Bulletin is the premier international peer reviewed journal on the latest science, technology and applications of gold. It includes papers on the latest research advances, state-of-the-art reviews, conference reports, book reviews and highlights of patents and scientific literature. Gold Bulletin does not publish manuscripts covering the snthesis of Gold nanoparticles in the presence of plant extracts or other nature-derived extracts. Gold Bulletin has been published over 40 years as a multidisciplinary journal read by chemists, physicists, engineers, metallurgists, materials scientists, biotechnologists, surface scientists, and nanotechnologists amongst others, both within industry and academia. Gold Bulletin is published in Association with the World Gold Council.
期刊最新文献
Efficacy of Au versus Au–Pd nanoparticles towards synthesis of spirooxindoles via multicomponent reaction 18 Karat yellow gold single-tracks manufactured by Laser Powder Bed Fusion (LPBF): 1 064 nm and 515 nm laser comparison Microbial-mediated synthesis of gold nanoparticles—current insights and future vistas Drug release properties of amphoteric HES/p(AETAC-co-IA) hydrogels decorated with gold nanoparticles Excited-state gold catalyzed activation of inert C–Cl bonds
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1