Diagnostic value of double-balloon enteroscopy and CT enterography for Crohn disease in intestine

Abstract

Objective To investigate the value of double-balloon enteroscopy and CT enterography for the diagnosis of intestinal Crohn disease(CD). Methods Data of 125 patients with suspected CD undergoing double-balloon enteroscopy and CT enterography were reviewed. Diagnosis was made based on pathological, endoscopic findings and clinic follow-up results. Detection rates and diagnostic rates of double-balloon enteroscopy and CT enterography for intestinal CD were compared. Results The detection and diagnostic rates of intestinal CD by double-balloon endoscopy were 62.4%(78/125)and 94.8% (74/78), respectively. The sensitivity, specificity and accuracy of double-balloon enteroscopy in the diagnosis of intestinal CD were 100.0%, 92.2% and 96.8%, respectively. The detection and diagnostic rates of intestinal CD by CT enterography were 44.8%(56/125) and 89.3% (50/56) , respectively. The sensitivity, specificity and accuracy of CT enterography in the diagnosis of intestinal CD were 67.6%, 88.2% and 76.0%, respectively. Both the detection rate and the diagnostic rate of double-balloon enteroscopy in intestinal CD were higher than those of CT enterography. Conclusion Double-balloon enteroscopy shows high application value for the diagnosis of intestinal CD, but CT enterography before enteroscopy can guide the selection of endoscopic approach, reduce economic expenditure and alleviate patients′ pain, so CT enterography could be the first choice for intestinal CD patients with contraindications of enteroscopy. Key words: Crohn disease; Diagnosis; Double-balloon enteroscopy; CT enterography