Jiacheng Tan, S. Shrestha, Panpan Wang, Jinjun Shi, Yanjia Lu, Qi Gao, Tong Lu, Ruihua Shi
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引用次数: 0
Abstract
Objective
To investigate the efficacy and safety of gastric peroral endoscopic myotomy (G-POEM) for postsurgical gastroparesis.
Methods
A retrospective analysis was performed on data of 47 patients with gastroparesis after subtotal gastrectomy, who underwent G-POEM at Zhongda Hospital Southeast University form August 2016 to June 2018. G-POEM procedure, complications related to G-POEM, and improvement of symptoms and gastric emptying function were observed.
Results
All patients underwent G-POEM successfully. No serious G-POEM-related complications were observed. During a follow-up period of 9.8±5.8 months (range 3-18 months), the scores of gastroparesis cardinal symptoms index (GCSI) were 1.6±0.5, 1.2±0.4, 1.1±0.6, 1.4±0.3 and 1.7±0.3 respectively at the 1st, 3rd, 6th, 12th, and 18th months after G-POEM, and all scores were lower than that before G-POEM (3.8±1.1, all P<0.01). The results showed the symptoms of gastroparesis were improved significantly. Gastric emptying imaging showed the hemi-emptying time was 23.8±8.8 min, 21.2±9.5 min, 20.9±8.3 min and 26.4±7.8 min at the 1st, 6th, 12th and 18th months after G-POEM, respectively, significantly shorter than that before G-POEM (67.8±12.5 min, all P<0.01). Three-dimensional ultrasonography results of gastric antrum volume showed that the hemi-emptying time was 26.4 (21.8, 40.3) min, 22.6 (13.9, 32.7) min, 24.3 (18.2, 36.5) min and 26.8 (16.4, 38.5) min at the 1st, 6th, 12th and 18th months after G-POEM, respectively, which were all significantly shorter than that before G-POEM [72.5 (48.3, 108.6) min, all P<0.01].
Conclusion
G-POEM has a satisfactory long-term efficacy on the treatment of gastroparesis after subtotal gastrectomy with good safety.
Key words:
Gastroparesis; Efficiency; Safety; Gastric peroral endoscopic myotomy
期刊介绍：
Chinese Journal of Digestive Endoscopy is a high-level medical academic journal specializing in digestive endoscopy, which was renamed Chinese Journal of Digestive Endoscopy in August 1996 from Endoscopy.
Chinese Journal of Digestive Endoscopy mainly reports the leading scientific research results of esophagoscopy, gastroscopy, duodenoscopy, choledochoscopy, laparoscopy, colorectoscopy, small enteroscopy, sigmoidoscopy, etc. and the progress of their equipments and technologies at home and abroad, as well as the clinical diagnosis and treatment experience.
The main columns are: treatises, abstracts of treatises, clinical reports, technical exchanges, special case reports and endoscopic complications.
The target readers are digestive system diseases and digestive endoscopy workers who are engaged in medical treatment, teaching and scientific research.
Chinese Journal of Digestive Endoscopy has been indexed by ISTIC, PKU, CSAD, WPRIM.
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