Bacterial colonization in atopic dermatitis

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Bali Medical Journal Pub Date : 2022-12-13 DOI:10.15562/bmj.v11i3.3811
D. A. Paramita, Khairina, N. Z. Lubis
{"title":"Bacterial colonization in atopic dermatitis","authors":"D. A. Paramita, Khairina, N. Z. Lubis","doi":"10.15562/bmj.v11i3.3811","DOIUrl":null,"url":null,"abstract":"Background: Atopic dermatitis (AD) is the most common skin disease in infants and children, influenced by hereditary and environmental factors and characterized by an inflammatory reaction in the skin. The increase in AD has been explained by two hypotheses: the \"hygiene hypothesis\" and the \"diet–microbiome hypothesis.\" AD is driven by a familial or personal predisposition to induce immunoglobulin E (IgE) antibodies and sensitize in response to stimuli. Microorganisms on the skin have been shown to play an important role in the pathogenesis of AD, and changes in the composition of the skin microbiome have been investigated in disease progression in pediatric AD patients.\nMethod: This descriptive observational study with a cross-sectional approach aims to determine the bacteria found in AD. The samples were taken from both the lesion and non-lesion areas in children with AD, which grown anaerobically and aerobically in blood and Brucella agar at 37C. The bacteri then indentified by Vitek® 2 and the data presented in percentage.\nResult: Thirty-five pediatric patients (18 males and 17 females) with a mean age of 7.58 (0,17 – 16) years were diagnosed with AD and were examined for bacterial culture on lesions and non-lesions. A total of 4 types of bacteria were found on the neck, 20 on the forearm, 2 on hand folds, 2 on fingers, 1 on the knee, and 5 on the lower limbs.\nConclusion: The most common bacteria were Gram-negative bacilli, namely, Acinetobacter baumannii (15%) and Burkholderia cepacian (14.3%), followed by the Gram-positive coccus Staphylococcus hominis (11.4%).","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bali Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15562/bmj.v11i3.3811","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 2

Abstract

Background: Atopic dermatitis (AD) is the most common skin disease in infants and children, influenced by hereditary and environmental factors and characterized by an inflammatory reaction in the skin. The increase in AD has been explained by two hypotheses: the "hygiene hypothesis" and the "diet–microbiome hypothesis." AD is driven by a familial or personal predisposition to induce immunoglobulin E (IgE) antibodies and sensitize in response to stimuli. Microorganisms on the skin have been shown to play an important role in the pathogenesis of AD, and changes in the composition of the skin microbiome have been investigated in disease progression in pediatric AD patients. Method: This descriptive observational study with a cross-sectional approach aims to determine the bacteria found in AD. The samples were taken from both the lesion and non-lesion areas in children with AD, which grown anaerobically and aerobically in blood and Brucella agar at 37C. The bacteri then indentified by Vitek® 2 and the data presented in percentage. Result: Thirty-five pediatric patients (18 males and 17 females) with a mean age of 7.58 (0,17 – 16) years were diagnosed with AD and were examined for bacterial culture on lesions and non-lesions. A total of 4 types of bacteria were found on the neck, 20 on the forearm, 2 on hand folds, 2 on fingers, 1 on the knee, and 5 on the lower limbs. Conclusion: The most common bacteria were Gram-negative bacilli, namely, Acinetobacter baumannii (15%) and Burkholderia cepacian (14.3%), followed by the Gram-positive coccus Staphylococcus hominis (11.4%).
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
特应性皮炎的细菌定植
背景:特应性皮炎(AD)是婴儿和儿童最常见的皮肤病,受遗传和环境因素的影响,以皮肤炎症反应为特征。阿尔茨海默病的增加可以用两种假说来解释:“卫生假说”和“饮食-微生物假说”。AD是由家族或个人倾向诱导免疫球蛋白E (IgE)抗体和敏感反应刺激驱动的。皮肤上的微生物已被证明在AD的发病机制中发挥重要作用,并且已经研究了儿童AD患者疾病进展中皮肤微生物组组成的变化。方法:本描述性观察性研究采用横断面方法,旨在确定在AD中发现的细菌。样本取自AD患儿的病变区和非病变区,分别在血液和琼脂布鲁氏菌37℃下进行厌氧和好氧生长。然后用Vitek®2鉴定细菌,并以百分比表示数据。结果:35例患儿(男18例,女17例),平均年龄7.58岁(0.17 ~ 16岁),诊断为AD,行病变和非病变细菌培养检查。颈部共检出4种细菌,前臂20种,手褶2种,手指2种,膝盖1种,下肢5种。结论:最常见的细菌为革兰氏阴性杆菌,分别为鲍曼不动杆菌(15%)和牛链球菌(14.3%),其次为革兰氏阳性球菌人型葡萄球菌(11.4%)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Bali Medical Journal
Bali Medical Journal MEDICINE, GENERAL & INTERNAL-
自引率
50.00%
发文量
8
审稿时长
3 weeks
期刊最新文献
The effect of fractionated ethanol red ginger (Zingiber officinale var. rubrum) extract on the pH level of Streptococcus gordonii metabolism (In-vitro Laboratory Experimental Research) Efficacy of combination therapy 5% permethrin cream and precipitated sulfur (ointment 2-4) compared with single therapy of 5% permethrin cream in children Hemangioma activity score evaluation in infantile hemangioma patients: a retrospective study Effect of Paraquat toxicity on lung and kidney organs on histopathological image assessment Mortality comparison between axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SND) among breast cancer pantient: A meta-analysis and systematic review study
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1