Frizka Eliza, M. Listiawan, Sawitri, Cita Rosita, Sigit Prakoeswa, Evy Ervianti, Budi Utomo, Erik Rizka Yulianggoro, Muhammad Yulianto, Listiawan
Introduction: Scabies is a skin infestation with the main pruritus symptom caused by Sarcoptes scabiei. The common complaints are discomfort due to itching and a picture of lesions on the skin in the form of papules, pustules, or vesicles. The study aims to analyze the comparative efficacy of using a combination therapy of 5% permethrin cream and precipitated sulfur (ointment 2-4) compared with single therapy of 5% permethrin cream in pediatric scabies patients at the Outpatient Clinic Dr. Soetomo General Academic Hospital in the 2019-2020 period. Methods: This study is an analytical study using a cross-sectional retrospective method, which aims to compare the effectiveness of using a combination of 5% permethrin cream and precipitated sulfur(ointment 2-4) compared to 5% permethrin cream as a single therapy. Study data were processed using SPSS, followed by univariate and bivariate analyses using statistical methods and comparative tests. Results: This study found 88 new scabies patients, with the number of patients who received permethrin single therapy as many as 43 patients (51.1%), while those who received combination therapy were 45 patients (48.9%). Scabies treatment using combination therapy has better effectiveness than single therapy 5% permethrin cream when seen from the absence of new complaints and improvement of skin lesions after receiving treatment. Analysis of therapy results for the emergence of new complaints with a p-value of 0.010 showed significant results. Analysis of the results of therapy seen in skin lesions improved on single therapy with a p-value of 0.014, indicating significant results. Conclusion: Significant results were found in the group that received combination therapy treatment seen from the improvement of skin lesions and no new lesions were found, while there were no significant comparison results when seen from complaints of itching
{"title":"Efficacy of combination therapy 5% permethrin cream and precipitated sulfur (ointment 2-4) compared with single therapy of 5% permethrin cream in children","authors":"Frizka Eliza, M. Listiawan, Sawitri, Cita Rosita, Sigit Prakoeswa, Evy Ervianti, Budi Utomo, Erik Rizka Yulianggoro, Muhammad Yulianto, Listiawan","doi":"10.15562/bmj.v13i1.5285","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5285","url":null,"abstract":"Introduction: Scabies is a skin infestation with the main pruritus symptom caused by Sarcoptes scabiei. The common complaints are discomfort due to itching and a picture of lesions on the skin in the form of papules, pustules, or vesicles. The study aims to analyze the comparative efficacy of using a combination therapy of 5% permethrin cream and precipitated sulfur (ointment 2-4) compared with single therapy of 5% permethrin cream in pediatric scabies patients at the Outpatient Clinic Dr. Soetomo General Academic Hospital in the 2019-2020 period.\u0000Methods: This study is an analytical study using a cross-sectional retrospective method, which aims to compare the effectiveness of using a combination of 5% permethrin cream and precipitated sulfur(ointment 2-4) compared to 5% permethrin cream as a single therapy. Study data were processed using SPSS, followed by univariate and bivariate analyses using statistical methods and comparative tests.\u0000Results: This study found 88 new scabies patients, with the number of patients who received permethrin single therapy as many as 43 patients (51.1%), while those who received combination therapy were 45 patients (48.9%). Scabies treatment using combination therapy has better effectiveness than single therapy 5% permethrin cream when seen from the absence of new complaints and improvement of skin lesions after receiving treatment. Analysis of therapy results for the emergence of new complaints with a p-value of 0.010 showed significant results. Analysis of the results of therapy seen in skin lesions improved on single therapy with a p-value of 0.014, indicating significant results.\u0000Conclusion: Significant results were found in the group that received combination therapy treatment seen from the improvement of skin lesions and no new lesions were found, while there were no significant comparison results when seen from complaints of itching","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140257977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Betadion Rizki Sinaredi, Dimas Prasetianto Wicaksono, Tania Saskianti, R. D. Ridwan, Muhammad Luthfi, Reinanda Pratiwi, Kittipong Laosuwan, P. Nuraini
Introduction: Oral health is important for the quality of human life, so maintaining oral health is necessary. However, many people have dental caries as one of the main diseases in the oral cavity. Dental caries can occur due to pH falling in the oral cavity by acid-producing bacteria, such as Streptococcus gordonii, which metabolizes sucrose as an energy source and produces lactic acid. Then, the environmental pH decreases. Chemicals are widely used as antibacterial agents, but long-term use can cause negative effects, hence antibacterial agents with minimal side effects are needed. Red ginger is one of the options that appears as a promising antibacterial agent. Even though a lot of research has been investigated regarding red ginger, there is limited information on the effect of fractionated red ginger extract on pH in bacterial metabolism, especially Streptococcus gordonii. This study aims to analyze the effect of the other components in red ginger besides its essential oil on the pH level of Streptococcus gordonii metabolism. Methods: The groups in this study are control group 1 (bacteria, BHIB), control 2 (bacteria, BHIB, 5% sucrose), and treatment groups (bacteria, BHIB, 5% sucrose, extract red ginger 1.56% and 0.78%). Data were analyzed with Duncan's One-Way ANOVA and Post-Hoc Multiple Comparison. Results: The pH level of control group 2 was lower than group control 1 and treatment groups (p<0.05). Conclusion: Fractionated ethanol extract of red ginger inhibits the decreasing pH level in the Streptococcus gordonii.
{"title":"The effect of fractionated ethanol red ginger (Zingiber officinale var. rubrum) extract on the pH level of Streptococcus gordonii metabolism (In-vitro Laboratory Experimental Research)","authors":"Betadion Rizki Sinaredi, Dimas Prasetianto Wicaksono, Tania Saskianti, R. D. Ridwan, Muhammad Luthfi, Reinanda Pratiwi, Kittipong Laosuwan, P. Nuraini","doi":"10.15562/bmj.v13i1.5283","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5283","url":null,"abstract":"Introduction: Oral health is important for the quality of human life, so maintaining oral health is necessary. However, many people have dental caries as one of the main diseases in the oral cavity. Dental caries can occur due to pH falling in the oral cavity by acid-producing bacteria, such as Streptococcus gordonii, which metabolizes sucrose as an energy source and produces lactic acid. Then, the environmental pH decreases. Chemicals are widely used as antibacterial agents, but long-term use can cause negative effects, hence antibacterial agents with minimal side effects are needed. Red ginger is one of the options that appears as a promising antibacterial agent. Even though a lot of research has been investigated regarding red ginger, there is limited information on the effect of fractionated red ginger extract on pH in bacterial metabolism, especially Streptococcus gordonii. This study aims to analyze the effect of the other components in red ginger besides its essential oil on the pH level of Streptococcus gordonii metabolism.\u0000Methods: The groups in this study are control group 1 (bacteria, BHIB), control 2 (bacteria, BHIB, 5% sucrose), and treatment groups (bacteria, BHIB, 5% sucrose, extract red ginger 1.56% and 0.78%). Data were analyzed with Duncan's One-Way ANOVA and Post-Hoc Multiple Comparison. \u0000Results: The pH level of control group 2 was lower than group control 1 and treatment groups (p<0.05). \u0000Conclusion: Fractionated ethanol extract of red ginger inhibits the decreasing pH level in the Streptococcus gordonii.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140256992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Putri Halla Shavira, M. Listiawan, Sawitri, C. Prakoeswa, Rahmadewi, L. Astari, Budi Utomo, Ni Putu Susari Widianingsih
Introduction: Infantile hemangioma (IH) is a benign vascular tumor commonly found in children. Generally, no special therapy is required because spontaneous resolutions occur. However, in some cases, therapy is required due to the potential of complications. During therapy, the side effects and effectiveness of therapy must be evaluated. One of the assessment tools is the Hemangioma Activity Score (HAS). HAS is a simple and objective assessment to evaluate the successful treatment of IH by observing swelling, color, and ulceration. The use of HAS in Indonesia is still minimal. This study aims to evaluate HAS before and after therapy in IH patients at Dr. Soetomo General Academic Hospital and Surabaya Skin Centre. Methods: Twenty-seven patient medical records were selected based on the inclusion and exclusion criteria. This study is an analytic cross-sectional retrospective using consecutive sampling. The collected data were tested for suitability using Cohen's Kappa. Pre- and post-tests were carried out using the Shapiro-Wilk and Wilcoxon tests afterward. Results: Among 27 IH cases occurred in females (81.4%), with the youngest age of the patient being 1 month and the oldest being 8 years. The onset of lesions in all patients appeared before 1 year of age. The most frequent location for IH lesions was the facial area (51.8%), with a clinical manifestation being plaque (37%). The most common therapy used in this study was pulse dye laser (PDL) (48.1%). Analysis of the difference in HAS before and after therapy showed p value = 0.00, a statistically significant difference in HAS before and after therapy. Conclusions: The hemangioma activity score is an effective measurement tool for measuring the severity of IH and evaluating the effectiveness of therapy.
简介婴儿血管瘤（IH）是一种常见于儿童的良性血管肿瘤。一般来说，不需要特殊治疗，因为会自然消退。但在某些情况下，由于可能出现并发症，需要进行治疗。在治疗过程中，必须对副作用和治疗效果进行评估。其中一种评估工具是血管瘤活动评分（HAS）。HAS 是一种简单而客观的评估方法，通过观察肿胀、颜色和溃疡情况来评估 IH 治疗是否成功。在印尼，HAS的使用仍然很少。本研究旨在评估苏托莫博士综合学术医院和泗水皮肤中心 IH 患者治疗前后的 HAS：根据纳入和排除标准选取了 27 份患者病历。本研究采用连续抽样法进行横断面回顾分析。使用科恩卡帕检验了所收集数据的适宜性。随后使用 Shapiro-Wilk 检验和 Wilcoxon 检验进行前后检验：在 27 例 IH 患者中，女性占 81.4%，年龄最小的 1 个月，最大的 8 岁。所有患者均在 1 岁前发病。IH 病变最常见的部位是面部（51.8%），临床表现为斑块（37%）。本研究中最常用的治疗方法是脉冲染料激光（PDL）（48.1%）。对治疗前后 HAS 差异的分析显示，P 值 = 0.00，治疗前后 HAS 差异具有统计学意义：血管瘤活动评分是衡量 IH 严重程度和评估治疗效果的有效测量工具。
{"title":"Hemangioma activity score evaluation in infantile hemangioma patients: a retrospective study","authors":"Putri Halla Shavira, M. Listiawan, Sawitri, C. Prakoeswa, Rahmadewi, L. Astari, Budi Utomo, Ni Putu Susari Widianingsih","doi":"10.15562/bmj.v13i1.5284","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5284","url":null,"abstract":"Introduction: Infantile hemangioma (IH) is a benign vascular tumor commonly found in children. Generally, no special therapy is required because spontaneous resolutions occur. However, in some cases, therapy is required due to the potential of complications. During therapy, the side effects and effectiveness of therapy must be evaluated. One of the assessment tools is the Hemangioma Activity Score (HAS). HAS is a simple and objective assessment to evaluate the successful treatment of IH by observing swelling, color, and ulceration. The use of HAS in Indonesia is still minimal. This study aims to evaluate HAS before and after therapy in IH patients at Dr. Soetomo General Academic Hospital and Surabaya Skin Centre.\u0000Methods: Twenty-seven patient medical records were selected based on the inclusion and exclusion criteria. This study is an analytic cross-sectional retrospective using consecutive sampling. The collected data were tested for suitability using Cohen's Kappa. Pre- and post-tests were carried out using the Shapiro-Wilk and Wilcoxon tests afterward.\u0000Results: Among 27 IH cases occurred in females (81.4%), with the youngest age of the patient being 1 month and the oldest being 8 years. The onset of lesions in all patients appeared before 1 year of age. The most frequent location for IH lesions was the facial area (51.8%), with a clinical manifestation being plaque (37%). The most common therapy used in this study was pulse dye laser (PDL) (48.1%). Analysis of the difference in HAS before and after therapy showed p value = 0.00, a statistically significant difference in HAS before and after therapy.\u0000Conclusions: The hemangioma activity score is an effective measurement tool for measuring the severity of IH and evaluating the effectiveness of therapy.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140258145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Eka Patri Yulianti, Habib Thariq Alfath, Syauqi Habibullah, Kartika Sari, M. Suzery, N. Susilaningsih, Suhartono, Endang Mahati, Ari Suwondo, U. Sadhana
Background: Paraquat is one of the active ingredients of the gramoxone type herbicide, which has very high toxicity so that it can cause poisoning and death. Paraquat causes direct cell damage by producing free radicals, which can cause pulmonary fibrosis and kidney failure. This study aims to analyze the effects of paraquat toxicity on the lungs and kidneys on histopathological features. Methods: This research is an experimental research post-test only control group design. The research subjects used stored biological material in the form of 12 lung and kidney organ samples from white rats (Rattus norvegicus) that had been treated in previous research, which were divided into 2 groups, namely the negative control group (P1, given distilled water), the positive control group (P2; given paraquat 0.01 gr/kgBW [single dose intraperitoneal]). All samples of stored biological material were made for lung and kidney preparations. The lung condition was assessed using the American Thoracic Society criteria, and the kidneys were evaluated using the Mitchell criteria with the help of the ImageJ application. Data were analyzed using the Kruskal-Wallis test and the Mann-Whitney test. Results: The Kruskal-Wallis test showed a significant difference in lung damage scores between groups with a p-value of 0.01 (p <0.005). The results of the Kruskal-Wallis test of the kidneys showed substantial differences in glomerular and proximal tubular damage scores between groups with p values of 0.004 and 0.009 (p <0.005). The results of the Mann-Whitney test also showed significant differences between groups P1 and P2 with a lung p value = 0.008 (p> 0.005) and kidney p = 0.009 (p > 0.005). Conclusion: In this study, it can be concluded that induction of paraquat 0.01 gr/kgBW causes changes in the histopathological appearance of the lungs and kidneys of white rats (Rattus norvegicus) in the form of lung and kidney damage as assessed by histopathological scores.
{"title":"Effect of Paraquat toxicity on lung and kidney organs on histopathological image assessment","authors":"Maria Eka Patri Yulianti, Habib Thariq Alfath, Syauqi Habibullah, Kartika Sari, M. Suzery, N. Susilaningsih, Suhartono, Endang Mahati, Ari Suwondo, U. Sadhana","doi":"10.15562/bmj.v13i1.5111","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5111","url":null,"abstract":"Background: Paraquat is one of the active ingredients of the gramoxone type herbicide, which has very high toxicity so that it can cause poisoning and death. Paraquat causes direct cell damage by producing free radicals, which can cause pulmonary fibrosis and kidney failure. This study aims to analyze the effects of paraquat toxicity on the lungs and kidneys on histopathological features.\u0000Methods: This research is an experimental research post-test only control group design. The research subjects used stored biological material in the form of 12 lung and kidney organ samples from white rats (Rattus norvegicus) that had been treated in previous research, which were divided into 2 groups, namely the negative control group (P1, given distilled water), the positive control group (P2; given paraquat 0.01 gr/kgBW [single dose intraperitoneal]). All samples of stored biological material were made for lung and kidney preparations. The lung condition was assessed using the American Thoracic Society criteria, and the kidneys were evaluated using the Mitchell criteria with the help of the ImageJ application. Data were analyzed using the Kruskal-Wallis test and the Mann-Whitney test.\u0000Results: The Kruskal-Wallis test showed a significant difference in lung damage scores between groups with a p-value of 0.01 (p <0.005). The results of the Kruskal-Wallis test of the kidneys showed substantial differences in glomerular and proximal tubular damage scores between groups with p values of 0.004 and 0.009 (p <0.005). The results of the Mann-Whitney test also showed significant differences between groups P1 and P2 with a lung p value = 0.008 (p> 0.005) and kidney p = 0.009 (p > 0.005).\u0000Conclusion: In this study, it can be concluded that induction of paraquat 0.01 gr/kgBW causes changes in the histopathological appearance of the lungs and kidneys of white rats (Rattus norvegicus) in the form of lung and kidney damage as assessed by histopathological scores.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140261679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alifia Ramadhani Herida, Sari Puspita Dewi, Akmal Fauzan Herida
Introduction: Axillary lymph node dissection (ALND) is a crucial surgical procedure for breast cancer. It has guaranteed locoregional control of the disease, guided adjuvant therapy, and functioned as a staging tool. However, over the past 25 years, a more conservative approach has become the standard for surgical management of the axilla. Because sentinel lymph node biopsy (SNB) is less invasive and less morbid than axillary lymph node dissection (ALND), it has become the standard surgical procedure for axillary staging of clinically node-negative breast cancer. This study aimed to compare the mortality of breast cancer patients receiving ALND and SNB procedure. Methods: Our review includes randomized controlled trials of breast cancer patients undergoing ALND or SNB surgical techniques. A systematic literature search was performed from PubMed on December 2023 to search for articles reporting on survival rates between ALND vs SNB among breast cancer patients. The data obtained then underwent statistical evaluation, and a meta-analysis was conducted using Review Manager 5.4. In order to represent primary outcomes, the risk ratio was estimated using an inverse variance technique with a random-effects model. Heterogeneity was presented with total values, 95% confidence intervals (CI), and I values. Results: As many as 208 articles were found in the PubMed database search, and only six studies were included in this study. The six included trials all used chemotherapy and radiotherapy for systematic treatment. The length of follow-up varied from 33 months to 15 years. The total number of patients in the trials was 3,585, and the study period was from 2011 to 2023. The pooled analysis of the mortality outcomes showed that the heterogeneity of the data was low (I2 21%, p = 0.4). In the pooled analysis, the mortality of patients with SNB for surgical treatment was not significantly different compared to patients with ALND (OR:0.88; 95% CI:0.65-1.19). Conclusion: The mortality of patients undergoing SNB and ALND does not differ significantly, according to this pooled study. It demonstrates that the group without axillary dissection had a primary survival outcome that was not inferior to that of the dissection group.
{"title":"Mortality comparison between axillary lymph node dissection (ALND) and sentinel lymph node biopsy (SND) among breast cancer pantient: A meta-analysis and systematic review study","authors":"Alifia Ramadhani Herida, Sari Puspita Dewi, Akmal Fauzan Herida","doi":"10.15562/bmj.v13i1.5265","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5265","url":null,"abstract":"Introduction: Axillary lymph node dissection (ALND) is a crucial surgical procedure for breast cancer. It has guaranteed locoregional control of the disease, guided adjuvant therapy, and functioned as a staging tool. However, over the past 25 years, a more conservative approach has become the standard for surgical management of the axilla. Because sentinel lymph node biopsy (SNB) is less invasive and less morbid than axillary lymph node dissection (ALND), it has become the standard surgical procedure for axillary staging of clinically node-negative breast cancer. This study aimed to compare the mortality of breast cancer patients receiving ALND and SNB procedure.\u0000Methods: Our review includes randomized controlled trials of breast cancer patients undergoing ALND or SNB surgical techniques. A systematic literature search was performed from PubMed on December 2023 to search for articles reporting on survival rates between ALND vs SNB among breast cancer patients. The data obtained then underwent statistical evaluation, and a meta-analysis was conducted using Review Manager 5.4. In order to represent primary outcomes, the risk ratio was estimated using an inverse variance technique with a random-effects model. Heterogeneity was presented with total values, 95% confidence intervals (CI), and I values.\u0000Results: As many as 208 articles were found in the PubMed database search, and only six studies were included in this study. The six included trials all used chemotherapy and radiotherapy for systematic treatment. The length of follow-up varied from 33 months to 15 years. The total number of patients in the trials was 3,585, and the study period was from 2011 to 2023. The pooled analysis of the mortality outcomes showed that the heterogeneity of the data was low (I2 21%, p = 0.4). In the pooled analysis, the mortality of patients with SNB for surgical treatment was not significantly different compared to patients with ALND (OR:0.88; 95% CI:0.65-1.19).\u0000Conclusion: The mortality of patients undergoing SNB and ALND does not differ significantly, according to this pooled study. It demonstrates that the group without axillary dissection had a primary survival outcome that was not inferior to that of the dissection group.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farhan Ali Husaini, Mohamad Izzur Maula, Muhammad Imam Ammarullah, I. Afif, M. D. P. Lamura, J. Jamari, T. Winarni
Introduction: This study presents a novel weighted vest integrated with vibrotactile stimulation for deep pressure therapy. Following the principles of Morrison's research, we assessed its effectiveness in calming users with four distinct vibration patterns. Method: Ten male participants without ASD history, aged 19-25 and weighing 48-73 kg, provided subjective evaluations using the Comfort Rating Scale (CRS). Result: Results showed that participants reported increased calmness after using the device, as evidenced by the overall ratings of the "calming" term, with the "down" pattern receiving the highest ratings. The study advocates for future work involving physiological sensors to measure the device's effectiveness objectively. While promising, this innovation has limitations, such as fixed vibration frequency and reliance on an adapter for power. Future iterations could address these issues to enhance the device's portability and customizable vibration frequencies. Conclusion: This research contributes to deep pressure therapy and vibration therapy by focusing on responsive patterns and subjective evaluations, opening doors for future developments.
{"title":"Control design of vibrotactile stimulation on weighted vest for deep pressure therapy","authors":"Farhan Ali Husaini, Mohamad Izzur Maula, Muhammad Imam Ammarullah, I. Afif, M. D. P. Lamura, J. Jamari, T. Winarni","doi":"10.15562/bmj.v13i1.4952","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.4952","url":null,"abstract":"Introduction: This study presents a novel weighted vest integrated with vibrotactile stimulation for deep pressure therapy. Following the principles of Morrison's research, we assessed its effectiveness in calming users with four distinct vibration patterns.\u0000Method: Ten male participants without ASD history, aged 19-25 and weighing 48-73 kg, provided subjective evaluations using the Comfort Rating Scale (CRS).\u0000Result: Results showed that participants reported increased calmness after using the device, as evidenced by the overall ratings of the \"calming\" term, with the \"down\" pattern receiving the highest ratings. The study advocates for future work involving physiological sensors to measure the device's effectiveness objectively. While promising, this innovation has limitations, such as fixed vibration frequency and reliance on an adapter for power. Future iterations could address these issues to enhance the device's portability and customizable vibration frequencies.\u0000Conclusion: This research contributes to deep pressure therapy and vibration therapy by focusing on responsive patterns and subjective evaluations, opening doors for future developments.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140434114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Systemic sclerosis or scleroderma is a rare disease with multiple complications which may include interstitial lung disease. The findings of diffuse type of systemic sclerosis, moderate restriction in pulmonary function test, interstitial pneumonia in chest x-ray, and ground glass opacity in thoracic CT-scan establish the diagnosis of interstitial lung disease associated with systemic sclerosis. We present a case of interstitial lung disease in a systemic sclerosis case, which was approached and treated comprehensively to slow the progression. Case Presentation: A 40-year-old female was admitted to the rheumatology polyclinic of Dr. Soetomo Hospital Surabaya with persistent dry cough for two years in June 2021. The patient also complained of breathlessness, painful joints, swollen knees, and morning stiffness three months prior to admission. The positive results of antinuclear antibody and rheumatoid factor were identified in 2016, which suggested autoimmune disease of scleroderma and being treated with azathioprine 50 mg twice a day, methylprednisolone 4 mg once a day, chloroquine 200 mg once a day, and calcium lactate once a day. The examinations in 2020 showed moderate restriction from the pulmonary function test, bilateral lung parenchymal infiltrates from the chest x-ray, and ground-glass opacity from the chest computed tomography scan (CT-scan). The patient was monthly prescribed cyclophosphamide 500 mg intravenously for six months as the substitution of azathioprine, methylprednisolone 4 mg once a day, and aspirin 100 mg once a day. The latest worsening condition led the patient to receive the substitution of cyclophosphamide which was mycophenolate mofetil 360 mg twice a day, along with aspirin 100mg and methylprednisolone 4 mg once a day, respectively. Conclusion: As a rare disease, the complications of systemic sclerosis should be anticipated. In this case, interstitial lung disease occurred following nearly five years of systemic sclerosis course which required immunosuppressive agents to enhance the efficacy of treatment. Comprehensive treatment with tight monitoring is necessary to slow the disease progression.
{"title":"Diagnostic approaches and treatments of systemic sclerosis patient with interstitial lung disease","authors":"Fauziah Diayu Retnaningtyas, Awalia","doi":"10.15562/bmj.v13i1.5225","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5225","url":null,"abstract":"Background: Systemic sclerosis or scleroderma is a rare disease with multiple complications which may include interstitial lung disease. The findings of diffuse type of systemic sclerosis, moderate restriction in pulmonary function test, interstitial pneumonia in chest x-ray, and ground glass opacity in thoracic CT-scan establish the diagnosis of interstitial lung disease associated with systemic sclerosis. We present a case of interstitial lung disease in a systemic sclerosis case, which was approached and treated comprehensively to slow the progression.\u0000Case Presentation: A 40-year-old female was admitted to the rheumatology polyclinic of Dr. Soetomo Hospital Surabaya with persistent dry cough for two years in June 2021. The patient also complained of breathlessness, painful joints, swollen knees, and morning stiffness three months prior to admission. The positive results of antinuclear antibody and rheumatoid factor were identified in 2016, which suggested autoimmune disease of scleroderma and being treated with azathioprine 50 mg twice a day, methylprednisolone 4 mg once a day, chloroquine 200 mg once a day, and calcium lactate once a day. The examinations in 2020 showed moderate restriction from the pulmonary function test, bilateral lung parenchymal infiltrates from the chest x-ray, and ground-glass opacity from the chest computed tomography scan (CT-scan). The patient was monthly prescribed cyclophosphamide 500 mg intravenously for six months as the substitution of azathioprine, methylprednisolone 4 mg once a day, and aspirin 100 mg once a day. The latest worsening condition led the patient to receive the substitution of cyclophosphamide which was mycophenolate mofetil 360 mg twice a day, along with aspirin 100mg and methylprednisolone 4 mg once a day, respectively.\u0000Conclusion: As a rare disease, the complications of systemic sclerosis should be anticipated. In this case, interstitial lung disease occurred following nearly five years of systemic sclerosis course which required immunosuppressive agents to enhance the efficacy of treatment. Comprehensive treatment with tight monitoring is necessary to slow the disease progression.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140434858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Neuropsychiatric systemic lupus erythematosus (NPSLE) is a complication of SLE involving the nervous and psychiatric systems with clinical manifestations including seizures, strokes, myelopathy, neuritis, meningitis, and psychosis. Seizures in NPSLE might be caused by intracranial infection, with bacteria as the most common pathogens. This study reported a rare case of seizure in a SLE patient due to invasive Candida infection. Case Presentation: A 26-year-old female presented in the emergency department of Dr. Soetomo Hospital Surabaya, Indonesia with seizure, which she has experienced in the last 2 days prior to hospital admission. She experienced a convulsion that lasted 5-10 minutes followed by loss of consciousness. The patient also complained of severe headaches two days before hospital admission. She was diagnosed with SLE in November 2022 and was currently taking methylprednisolone. Physical examination showed Glasgow Coma Scale (GCS) of E3V4M5, fever, dyspnea, and rough rhonchi on the right lung. Chest X-ray indicated pneumonia, while brain computed tomography (CT) suggested subacute to chronic thromboembolism. The patient was diagnosed with NPSLE due to intracranial infection, and hospital-acquired pneumonia (HAP), and was given Levofloxacin. On the 3rd day, a reddish lesion with central healing was found on the cheeks, and the patient had dyspnea, suggesting fungi infection. Methylprednisolone was stopped while fluconazole and urine cultures were initiated. Urine culture suggested Fluconazole-sensitive Candida and consultation with a dermato-venerologist confirmed Candida, thus, Fluconazole was continued along with dexamethasone, and Levofloxacin. The patient showed clinical improvement and was discharged after 12 days. Conclusion: Seizure is one of the most common manifestations of NPSLE, due to intracranial infection. Although rare, we cannot rule out the possibility of fungal infection in NPSLE patients with intracranial infection. Early diagnosis and prompt treatment are critical for better prognosis, as shown in this patient.
{"title":"Invasive candida infection as the cause of seizure in a patient with systemic lupus erythematosus: a report of unusual case","authors":"Mirza Suryo Adi, A. Awalia","doi":"10.15562/bmj.v13i1.5135","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5135","url":null,"abstract":"Background: Neuropsychiatric systemic lupus erythematosus (NPSLE) is a complication of SLE involving the nervous and psychiatric systems with clinical manifestations including seizures, strokes, myelopathy, neuritis, meningitis, and psychosis. Seizures in NPSLE might be caused by intracranial infection, with bacteria as the most common pathogens. This study reported a rare case of seizure in a SLE patient due to invasive Candida infection.\u0000Case Presentation: A 26-year-old female presented in the emergency department of Dr. Soetomo Hospital Surabaya, Indonesia with seizure, which she has experienced in the last 2 days prior to hospital admission. She experienced a convulsion that lasted 5-10 minutes followed by loss of consciousness. The patient also complained of severe headaches two days before hospital admission. She was diagnosed with SLE in November 2022 and was currently taking methylprednisolone. Physical examination showed Glasgow Coma Scale (GCS) of E3V4M5, fever, dyspnea, and rough rhonchi on the right lung. Chest X-ray indicated pneumonia, while brain computed tomography (CT) suggested subacute to chronic thromboembolism. The patient was diagnosed with NPSLE due to intracranial infection, and hospital-acquired pneumonia (HAP), and was given Levofloxacin. On the 3rd day, a reddish lesion with central healing was found on the cheeks, and the patient had dyspnea, suggesting fungi infection. Methylprednisolone was stopped while fluconazole and urine cultures were initiated. Urine culture suggested Fluconazole-sensitive Candida and consultation with a dermato-venerologist confirmed Candida, thus, Fluconazole was continued along with dexamethasone, and Levofloxacin. The patient showed clinical improvement and was discharged after 12 days.\u0000Conclusion: Seizure is one of the most common manifestations of NPSLE, due to intracranial infection. Although rare, we cannot rule out the possibility of fungal infection in NPSLE patients with intracranial infection. Early diagnosis and prompt treatment are critical for better prognosis, as shown in this patient.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunanto Kurnia, Trianingsih Trianingsih, Tandean Tommy Novenanto, S. Supomo, Haryo Aribowo, Yuletta Adny Ambarsari, Ihsanul Amal
Link of Video Abstract: https://youtu.be/MSeO8kuKhGc Introduction: The preferred vascular access for hemodialysis in chronic kidney disease patients is the arteriovenous fistula (AVF). It is recommended to create AVFs as distally as possible. The snuffbox, situated at the far end of the wrist, is infrequently utilized for AVF insertion due to the prevalent smaller vessel calibers. Case: This case series involves seven patients with chronic kidney disease scheduled for first AVF placement in the snuffbox region, with an average age of 56.71 years. All patients showed an average radial artery caliber of 20.3mm, a mean peak systolic velocity of 67.14 cm/s, and a cephalic vein caliber of 22.7mm, according to preoperative vascular ultrasound. The AVF placement involved an end-to-side anastomosis. All patient demonstrated anastomosis clinical maturation, the primary patency rate was 86%. Follow-up Doppler examinations revealed that patients achieving functional patency had an average caliber of 5.22mm and an average flow rate of 810.65 ml/s. Conclusion: SAVF are created less frequently due to predominantly smaller vessel caliber. However, it can be a viable alternative site for fistula implantation. Vascular mapping is required to ensure that both vessels have minimum 2 mm caliber. Maturation in SAVF have comparable results with the other sites.
{"title":"Follow-up evaluation of snuffbox arteriovenous fistula as an alternative site for hemodialysis - a case series in a lower-middle country","authors":"Yunanto Kurnia, Trianingsih Trianingsih, Tandean Tommy Novenanto, S. Supomo, Haryo Aribowo, Yuletta Adny Ambarsari, Ihsanul Amal","doi":"10.15562/bmj.v13i1.5161","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5161","url":null,"abstract":"Link of Video Abstract: https://youtu.be/MSeO8kuKhGc\u0000 \u0000Introduction: The preferred vascular access for hemodialysis in chronic kidney disease patients is the arteriovenous fistula (AVF). It is recommended to create AVFs as distally as possible. The snuffbox, situated at the far end of the wrist, is infrequently utilized for AVF insertion due to the prevalent smaller vessel calibers.\u0000 Case: This case series involves seven patients with chronic kidney disease scheduled for first AVF placement in the snuffbox region, with an average age of 56.71 years. All patients showed an average radial artery caliber of 20.3mm, a mean peak systolic velocity of 67.14 cm/s, and a cephalic vein caliber of 22.7mm, according to preoperative vascular ultrasound. The AVF placement involved an end-to-side anastomosis. All patient demonstrated anastomosis clinical maturation, the primary patency rate was 86%. Follow-up Doppler examinations revealed that patients achieving functional patency had an average caliber of 5.22mm and an average flow rate of 810.65 ml/s.\u0000 Conclusion: SAVF are created less frequently due to predominantly smaller vessel caliber. However, it can be a viable alternative site for fistula implantation. Vascular mapping is required to ensure that both vessels have minimum 2 mm caliber. Maturation in SAVF have comparable results with the other sites.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Leprosy is a chronic granulomatous disease affecting mainly the skin and peripheral nerves caused by the obligate intracellular pathogen Mycobacterium leprae. This study aimed to determine the relationship between Leprosy Suspicion Questionnaire (LSQ) and anti-PGL-1 IgM antibody levels in household contacts of leprosy patients. Methods: This research was an observational analytical study with a cross-sectional design. The sample consisted of 30 subjects who were household contacts of leprosy patients. Anti-PGL-1 IgM antibody levels were examined using the ELISA method at the Cito Laboratory, Yogyakarta. Results: Regarding demographic characteristics, there were 18 female subjects (60%) and 12 male subjects (40%). LSQ+ results were found in 22 (73.3%) subjects, while LSQ- results were found in 8 (26.7%) subjects. The results of the anti-PGL-1 IgM examination were classified into three categories, namely seronegative (<605 U/ mL) totaling 25 people (83.3%), low titer seropositivity (605–1000 U/mL) totaling four people (13.3 %), and high titer seropositivity (>1000 U/mL) was one person (3.3%). The mean value of IgM anti-PGL-1 was 383.63 U/mL, with the lowest value being 0 and the highest being 1593 U/mL. Using Fischer's Exact showed no relationship between LSQ and IgM Anti-PGL-1 (p=0.287). Conclusions: No relationship was found between LSQ and anti-PGL-1 IgM antibody levels in household contacts of leprosy patients. The results of the LSQ answers correlated with anti-PGL-1 IgM antibodies found in only five subjects.
{"title":"Relationship between Leprosy Suspicion Questionnaire with IgM anti-PGL-1 antibody levels in household contacts of leprosy","authors":"Mutia Fadhila Sy, R. Lubis, Kristina Nadeak","doi":"10.15562/bmj.v13i1.5052","DOIUrl":"https://doi.org/10.15562/bmj.v13i1.5052","url":null,"abstract":"Introduction: Leprosy is a chronic granulomatous disease affecting mainly the skin and peripheral nerves caused by the obligate intracellular pathogen Mycobacterium leprae. This study aimed to determine the relationship between Leprosy Suspicion Questionnaire (LSQ) and anti-PGL-1 IgM antibody levels in household contacts of leprosy patients.\u0000Methods: This research was an observational analytical study with a cross-sectional design. The sample consisted of 30 subjects who were household contacts of leprosy patients. Anti-PGL-1 IgM antibody levels were examined using the ELISA method at the Cito Laboratory, Yogyakarta.\u0000Results: Regarding demographic characteristics, there were 18 female subjects (60%) and 12 male subjects (40%). LSQ+ results were found in 22 (73.3%) subjects, while LSQ- results were found in 8 (26.7%) subjects. The results of the anti-PGL-1 IgM examination were classified into three categories, namely seronegative (<605 U/ mL) totaling 25 people (83.3%), low titer seropositivity (605–1000 U/mL) totaling four people (13.3 %), and high titer seropositivity (>1000 U/mL) was one person (3.3%). The mean value of IgM anti-PGL-1 was 383.63 U/mL, with the lowest value being 0 and the highest being 1593 U/mL. Using Fischer's Exact showed no relationship between LSQ and IgM Anti-PGL-1 (p=0.287).\u0000Conclusions: No relationship was found between LSQ and anti-PGL-1 IgM antibody levels in household contacts of leprosy patients. The results of the LSQ answers correlated with anti-PGL-1 IgM antibodies found in only five subjects.","PeriodicalId":44369,"journal":{"name":"Bali Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140461579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：