Dental considerations in patients on antiplatelet and anticoagulant drugs – Clearing the fog: A case series

P. Jain, A. Jain, Madhvika Patidar, R. Banthia, P. Batham
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Abstract

The use of antiplatelet and anticoagulant drugs is increasing day by day. Hence, recently dentists are coming across a greater number of patients on such medications. Dentists should have in-depth knowledge about the indications, bleeding complications, postoperative instructions, and antidotes of these drugs on oral health and therapy. The dental surgeon should also be aware of the consequences of withdrawal or continuation of these drugs on life-threatening thromboembolic events or bleeding complications. The present observational study included 1240 cardiac patients who were on antithrombotic therapy. Out of which 78 patients underwent various dental procedures involving probable bleeding complications, 11 patients met with bleeding complications, and 2 patients of which reported spontaneous bleeding. This case series reports bleeding complications associated with dental procedures (either procedure-related or spontaneous oral bleeding) in patients with drug-induced coagulopathies (patients either on antiplatelet or anticoagulant or on both). A description of the medical conditions of these patients along with a regimen of antithrombotic therapy is discussed. Management of bleeding complications is also described. These case series recommend continuing antiplatelet or anticoagulant therapy during dental procedures to prevent the risk of life-threatening conditions owing to thromboembolic complications. Simultaneously, the necessary armamentarium to deal with bleeding complications should be readily available.
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使用抗血小板和抗凝血药物的患者的牙科注意事项-清除迷雾:一个病例系列
抗血小板和抗凝血药物的使用日益增加。因此,最近牙医遇到越来越多的病人服用这类药物。牙医应深入了解这些药物的适应症、出血并发症、术后指示和解毒剂对口腔健康和治疗的影响。牙科医生也应该意识到停药或继续使用这些药物对危及生命的血栓栓塞事件或出血并发症的后果。目前的观察性研究包括1240例接受抗血栓治疗的心脏病患者。其中78名患者接受了可能出现出血并发症的各种牙科手术,11名患者出现出血并发症,2名患者报告自发性出血。本病例系列报告了与牙科手术相关的出血并发症(手术相关或自发口腔出血)在药物诱导的凝血功能障碍患者中(患者使用抗血小板或抗凝剂或两者)。对这些患者的医疗条件以及抗血栓治疗方案的描述进行了讨论。出血并发症的管理也被描述。这些病例系列建议在牙科手术期间继续进行抗血小板或抗凝治疗,以防止因血栓栓塞并发症而危及生命的危险。同时,处理出血并发症的必要设备应随时可用。
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