Synthesis and characterization of ZnO/β-cyclodextrin/nicotinic acid nanocomposite and its biological and environmental application

IF 3.8 4区工程技术 Q2 CHEMISTRY, MULTIDISCIPLINARY Green Processing and Synthesis Pub Date : 2023-01-01 DOI:10.1515/gps-2023-0050

Mohammed S. Alqahtani, Rabbani Syed, Mudassar Shahid, J. Shaik

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引用次数: 1

Abstract

Abstract In the present work, the disk-shaped zinc oxide (ZnO) nanoparticles were synthesized and functionalized with β-cyclodextrin (β-CD) and nicotinic acid (vitamin B3) using the wet co-precipitation method. The functionalized ZnO/β-CD/nicotinic acid nanocomposite materials were characterized using UV-visible spectroscopy (UV-Vis), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), energy dispersive spectroscopy (EDS), field emission electron microscopy (FESEM), and band-gap energy analysis. The band gap value (E g) was 4.3 eV. The average XRD crystallite size was determined using the Scherrer formula and was found to be 50 nm. The ZnO/β-CD/nicotinic acid nanocomposite material showed a photocatalytic effect for dye-polluted wastewater. It also showed an antibacterial effect against the Gram-positive bacterial strain Streptococcus aureus (S. aureus) but did not show any antibacterial activity with Gram-negative Escherichia coli (E. coli). The ZnO/β-CD/nicotinic acid nanocomposite also showed antifungal activity with Aspergillus niger (A. niger). It was noticed that ZnO/β-CD/nicotinic acid nanocomposite showed efficient anticancer activity with IC50 = 14.95 µg·mL−1 in MCF-7 cell lines. Because of the formation of singlet oxygen (O2˙−) and hydrogen oxide radical (–OH˙), the composite material showed a photodegradation reaction against aq. solution of methylene blue dye. After 190 min, the blue colour of aq. solution methylene blue was decolourized at 6 pH at a constant time interval.

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ZnO/β-环糊精/烟酸纳米复合材料的合成、表征及其生物和环境应用

摘要本文采用湿共沉淀法合成了圆盘状氧化锌纳米颗粒，并以β-环糊精(β-CD)和烟酸(维生素B3)进行了功能化。采用紫外可见光谱(UV-Vis)、傅里叶变换红外光谱(FTIR)、x射线衍射(XRD)、能谱(EDS)、场发射电子显微镜(FESEM)和带隙能量分析对功能化ZnO/β-CD/烟酸纳米复合材料进行了表征。带隙值(eg)为4.3 eV。采用Scherrer公式测定XRD平均晶粒尺寸为50 nm。ZnO/β-CD/烟酸纳米复合材料对染料污染废水具有良好的光催化作用。它对革兰氏阳性菌株金黄色链球菌(S. aureus)也有抗菌作用，但对革兰氏阴性大肠杆菌(E. coli)没有任何抗菌活性。ZnO/β-CD/烟酸纳米复合材料对黑曲霉(A. niger)也表现出抗真菌活性。结果表明，ZnO/β-CD/烟酸纳米复合材料在MCF-7细胞株中具有良好的抗癌活性，IC50值为14.95µg·mL−1。由于单线态氧(O2˙−)和氧化氢自由基(oh˙)的形成，该复合材料对亚甲基蓝染料水溶液表现出光降解反应。190 min后，在6 pH条件下，以恒定的时间间隔对水溶液亚甲基蓝进行脱色。

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来源期刊

Green Processing and Synthesis CHEMISTRY, MULTIDISCIPLINARY-ENGINEERING, CHEMICAL

CiteScore

6.70

自引率

9.30%

发文量

审稿时长

7 weeks

期刊介绍： Green Processing and Synthesis is a bimonthly, peer-reviewed journal that provides up-to-date research both on fundamental as well as applied aspects of innovative green process development and chemical synthesis, giving an appropriate share to industrial views. The contributions are cutting edge, high-impact, authoritative, and provide both pros and cons of potential technologies. Green Processing and Synthesis provides a platform for scientists and engineers, especially chemists and chemical engineers, but is also open for interdisciplinary research from other areas such as physics, materials science, or catalysis.