M. Truong, Mai Lan Huong, N. Anh, S. Shen, P. Khang
{"title":"Inhibitory Effects and Caspase 3 Activation Activity of Natural Compounds from Anemarrhena Asphodeloides (Bunge) Rhizomes in Vietnam","authors":"M. Truong, Mai Lan Huong, N. Anh, S. Shen, P. Khang","doi":"10.1080/22311866.2021.1919207","DOIUrl":null,"url":null,"abstract":"Abstract Three compounds were identified from the ethanolic extract of Anemarrhena asphodeloides Bunge (A. asphodeloides) plant using silica gel chromatography. Their structures were confirmed by NMR and MS data analysis. The inhibitory activities against the MCF7 cancer cell line were evaluated and study the caspase 3 activation activity. Compound 3 exhibited good inhibitory activity and caspase 3 activation activity on the MCF7 cell line.","PeriodicalId":15364,"journal":{"name":"Journal of Biologically Active Products from Nature","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2021-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/22311866.2021.1919207","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biologically Active Products from Nature","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/22311866.2021.1919207","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Three compounds were identified from the ethanolic extract of Anemarrhena asphodeloides Bunge (A. asphodeloides) plant using silica gel chromatography. Their structures were confirmed by NMR and MS data analysis. The inhibitory activities against the MCF7 cancer cell line were evaluated and study the caspase 3 activation activity. Compound 3 exhibited good inhibitory activity and caspase 3 activation activity on the MCF7 cell line.
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