Biological Activity Evaluation of Scorzonera tomentosa

Gülşen Güçlü, Nuraniye Eruygur, E. Uçar, Dilara ÜLGER ÖZBEK, Halil Bal, Aşkın Akpolat, D. Kahrizi
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Abstract

This study, it was aimed to evaluate the phytochemical components, antimicrobial activity and antioxidant activity of 80% ethanol extract of Scorzonera tomentosa, an endemic species. The major component of the plant was determined by GC-MS analysis and was found as 2-Pentanamine (35.68%). When the antioxidant capacity of S.tomentosa was examined, DPPH and ABTS radical scavenging activities were determined to be quite high compared to the reference drug (IC50 values; DPPH: 517.0 ± 1.86 µg/mL; ABTS: 244.8 ± 0.94 µg/mL; reference drug: 1.313 ± 0.24 µg/mL). In addition, according to total phenol content (TPC) and total flavonoid content (TFC) analyses, it was determined that the plant is richer in flavonoids. The antimicrobial activity of this species is not at an effective level. More extensive studies with S.tomentosa may allow the plant to be used as a natural antioxidant.
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毛Scorzonera的生物活性评价
本研究旨在对中国特有植物毛毡绵(Scorzonera tomentosa) 80%乙醇提取物的植物化学成分、抑菌活性和抗氧化活性进行研究。气相色谱-质谱法测定其主要成分为2-戊胺(35.68%)。当检测毛毛菌的抗氧化能力时,测定其DPPH和ABTS自由基清除能力与参比药物相比相当高(IC50值;DPPH: 517.0±1.86µg/mL;ABTS: 244.8±0.94µg/mL;标准药物:1.313±0.24µg/mL)。此外,根据总酚含量(TPC)和总黄酮含量(TFC)分析,确定该植物含有丰富的黄酮类化合物。该物种的抗菌活性未达到有效水平。对绒毛草进行更广泛的研究可能会使这种植物被用作天然抗氧化剂。
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审稿时长
24 weeks
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