Prevalence, Risk Factors and Complications of Preeclampsia at Rafidia Governmental Surgical Hospital in Palestine: Case-Control Study

Q3 Pharmacology, Toxicology and Pharmaceutics Jordan Journal of Pharmaceutical Sciences Pub Date : 2023-07-24 DOI:10.35516/jjps.v16i2.1495
Iyad Ali
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Abstract

The development of hypertensive disorders is the most common medical complication during pregnancy. Preeclampsia (PE) causes multi-organ dysfunction and can lead to premature delivery, fetal death, and permanent organ damage in women. The purpose of this study is to estimate the prevalence of PE among the pregnant women who were followed at Rafidia Governmental Surgical Hospital (RGSH) in Nablus-Palestine for a year period from October 2020 to October 2021. During that period, we carried out an observational case-control study and assessed the risk factors, complications, and PE management in RGSH. The study included 170 patients with 85 preeclamptic and 85 randomly selected non-preeclamptic women from 5462 deliveries. PE group age ranged from 17 to 45 years old. PE prevalence increased with increasing gestational age (24% and 75% among women who were <37 and ≥ 37 of age, respectively), where maternal age and abortion incidents were associated with severe PE. First or multiple pregnancies were also factors linked to severe PE. Our findings support the body of evidence that PE is considered as a preventable high causative risk of fetal mortality and morbidity.
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巴勒斯坦Rafidia政府外科医院先兆子痫的患病率、危险因素和并发症:病例对照研究
高血压疾病的发展是妊娠期最常见的医疗并发症。先兆子痫(PE)会导致多器官功能障碍,并可能导致早产、胎儿死亡和女性永久性器官损伤。本研究的目的是评估2020年10月至2021年10月在巴勒斯坦纳布卢斯Rafidia政府外科医院(RGSH)随访一年的孕妇PE的患病率。在此期间,我们进行了一项观察性病例对照研究,并评估了RGSH的危险因素、并发症和PE管理。这项研究包括170名患者,85名先兆子痫患者和从5462名分娩中随机选择的85名非先兆子痫妇女。PE组年龄17~45岁。PE患病率随着孕龄的增加而增加(<37岁和≥37岁的女性分别为24%和75%),其中母亲年龄和堕胎事件与严重PE有关。首次或多次妊娠也是与严重PE相关的因素。我们的研究结果支持了大量证据,即PE被认为是一种可预防的胎儿死亡率和发病率的高致病风险。
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来源期刊
Jordan Journal of Pharmaceutical Sciences
Jordan Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
1.70
自引率
0.00%
发文量
33
期刊介绍: The Jordan Journal of Pharmaceutical Sciences (JJPS) is a scientific, bi-annual, peer-reviewed publication that will focus on current topics of interest to the pharmaceutical community at large. Although the JJPS is intended to be of interest to pharmaceutical scientists, other healthy workers, and manufacturing processors will also find it most interesting and informative. Papers will cover basic pharmaceutical and applied research, scientific commentaries, as well as views, reviews. Topics on products will include manufacturing process, quality control, pharmaceutical engineering, pharmaceutical technology, and philosophies on all aspects of pharmaceutical sciences. The editorial advisory board would like to place an emphasis on new and innovative methods, technologies, and techniques for the pharmaceutical industry. The reader will find a broad range of important topics in this first issue.
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