Drug Utilization Pattern by Using WHO Core Prescribing Indicators in Orthopedics and Obstetrics / Gynecology Departments of a Tertiary Care Hospital

Naresh Karki, R. Joshi, B. K. Shrestha, Pravin Prasad
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引用次数: 5

Abstract

Introduction: Drug utilization research is an important tool to facilitate rational use of drugs. In low income countries irrational use of drugs is a common problem like overuse of drugs and inappropriate use of antibiotics, leading to poor treatment outcome and increased burden of treatment. This study was conducted to provide understanding of drug utilization pattern by using WHO Core Prescribing Indicator. Methods: This study was conducted in Orthopedics and Obstetrics / Gynecology departments. Patients visiting these Out Patient Departments with at least one drug on prescription form were included in the study. Further, information related to WHO Core Prescribing Indicators were collected in pre-designed proforma. Results: Average number of drugs prescribed per prescription was 2.6. Means of number of drugs prescribed in Orthopedics and Obstetrics / Gynecology departments were 2.9 and 2.3 respectively (p < 0.001). Drugs prescribed in generic name and from essential drug list was 41.4% and 34.3% respectively. Prescription forms with generic name in Orthopedics department were significantly more compared to Obstetrics / Gynecology department (p = 0.00002). However, there was an increased tendency to prescribe drugs from essential drug list in Obstetrics / Gynecology department compared to Orthopedics department (p < 0.001). Conclusion: Drugs were prescribed by generic name and from essential drug list, but this was not sufficient to meet the ideal values of WHO Core Prescribing Indicator. Therefore, prioritization on prescribing drugs by generic name and from essential drug list by respective departments to achieve the standards of WHO needs to be encouraged.
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某三级医院骨科和妇产科使用WHO核心处方指标的药物利用模式
药物利用研究是促进合理用药的重要工具。在低收入国家,不合理使用药物与过度使用药物和不适当使用抗生素一样,是一个普遍存在的问题,导致治疗效果差,增加了治疗负担。本研究旨在通过使用世卫组织核心处方指标来了解药物利用模式。方法:本研究在骨科和妇产科进行。就诊于这些门诊部且处方上至少有一种药物的患者被纳入研究。此外,以预先设计的形式收集了与世卫组织核心处方指标有关的信息。结果:每张处方的平均处方药品数为2.6种。骨科和妇产科的平均处方药物数分别为2.9和2.3种(p < 0.001)。仿制药和基本药物目录中使用的药物比例分别为41.4%和34.3%。骨科使用通用名的处方单明显多于妇产科(p = 0.00002)。然而,与骨科相比,产科/妇科的基本药物处方倾向增加(p < 0.001)。结论:以通用名和基本药物清单开具处方,不足以满足WHO核心处方指标的理想值。因此,需要鼓励各部门优先按通用名和基本药物清单开药,以达到世卫组织的标准。
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