PD51-11 REPORTING RADICAL CYSTECTOMY OUTCOMES FOLLOWING IMPLEMENTATION OF ENHANCED RECOVERY AFTER SURGERY (ERAS) PROTOCOLS

Abstract

UCB had a higher frequency of stage pT3 (odds ratio [OR], 3.84; 95% confidence interval [CI], 1.63e9.03; p[0.002) and risk of lymph node metastasis (OR, 2.58; 95% CI, 1.15e5.76; p[0.02), ureteral marginpositive (OR 12.18; 95% CI, 4.62e32.13; p<0.00001), and perivesical soft tissue margin-positive (OR 12.31; 95% CI, 5.15e29.41; p<0.00001) status after radical cystectomy than those with C-UCB. Although there was no difference in CSM (hazard ratio [HR], 1.40; 95% CI, 0.82e2.40; p[0.22) between PV-UCB and C-UCB, PV-UCB had worse survival outcomes (OM) than C-UCB approaching the borderline of significance (HR, 1.62; 95% CI, 0.98e2.68; p[0.06) when adjusted for other clinicopathological characteristics. CONCLUSIONS: PV-UCB was strongly associated with adverse clinicopathological features and worse OM compared to CUCB after adjusting other clinicopathological parameters, and PV histology of UCB is an independent prognostic factor for overall survival.