Molecular Genetic of Hemochromatosis Disease using Bioinformatics Tools

R. K. Mishra
{"title":"Molecular Genetic of Hemochromatosis Disease using Bioinformatics Tools","authors":"R. K. Mishra","doi":"10.21786/bbrc/15.3.7","DOIUrl":null,"url":null,"abstract":"Hemochromatosis is caused by p.Cys282Tyr mutations in HFE. This study’s objective was to find causal or disease-related variations in people with erythrocytosis of unknown origin who came from a family with clear blood markers and other indicators of congenital erythrocytosis. This research aims to create a new hemochromatosis risk prediction prototype and evaluate psychographic, clinical, and genomic data to improve predictive model performance. In this review, a conditional characterization of primary iron overload, secondary iron overload, and hemochromatosis medical history is established, as well as an analysis of the drug molecules used to treat hemochromatosis. This paper provides Hemochromatosis Gene brand and its operation.","PeriodicalId":9156,"journal":{"name":"Bioscience Biotechnology Research Communications","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioscience Biotechnology Research Communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21786/bbrc/15.3.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Hemochromatosis is caused by p.Cys282Tyr mutations in HFE. This study’s objective was to find causal or disease-related variations in people with erythrocytosis of unknown origin who came from a family with clear blood markers and other indicators of congenital erythrocytosis. This research aims to create a new hemochromatosis risk prediction prototype and evaluate psychographic, clinical, and genomic data to improve predictive model performance. In this review, a conditional characterization of primary iron overload, secondary iron overload, and hemochromatosis medical history is established, as well as an analysis of the drug molecules used to treat hemochromatosis. This paper provides Hemochromatosis Gene brand and its operation.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
应用生物信息学工具进行血色素沉着病的分子遗传学研究
血色素沉着症是由HFE中的p.Cys282Tyr突变引起的。这项研究的目的是寻找来源不明的红细胞增多症患者的病因或疾病相关变异,这些患者来自一个具有明确血液标志物和其他先天性红细胞增多指标的家庭。本研究旨在创建一个新的血色素沉着症风险预测原型,并评估心理、临床和基因组数据,以提高预测模型的性能。在这篇综述中,建立了原发性铁过载、继发性铁过载和血色素沉着症病史的条件表征,以及用于治疗血色素沉着病的药物分子的分析。本文介绍了血色素沉着症基因品牌及其运作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Bioscience Biotechnology Research Communications
Bioscience Biotechnology Research Communications BIOTECHNOLOGY & APPLIED MICROBIOLOGY-
自引率
0.00%
发文量
73
期刊最新文献
Standardization and Evaluation of Buffers: A One Step DNA Extraction Protocol from Microbial Cultures Adsorption of Phenol and Resorcinol on Parthenium Based Activated Carbon (Pac) in Basal Salt Medium: Equilibrium and Kinetics Localization of NPY Immunoreactivity in the Proximal and Distal Intestinal Region of Teleost Fish, Notopterus Ecology of Biofouling Phytoplankton in Chinnamuttom Harbour Waters Southeast Coast of India Avifaunal Abundance of Lumding Forest Reserve Area, Assam, India
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1