Innate immune cell and severe acute respiratory syndrome coronavirus 2 interaction

N. Cortes-Perez
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Abstract

Coronavirus disease caused by the recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a major public health that has submerged the world into a crisis unprecedented in the modern era. A better understanding of the innate immune response could help to fight this pandemic and be better prepared for potential future outbreaks. Interestingly, innate immune cells can develop a non-specific memory termed trained immunity. This review details recent evidence concerning the interaction of SARS-CoV-2 with innate immune cells, in particular those in which the trained immunity activity has been demonstrated.
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先天免疫细胞与严重急性呼吸综合征冠状病毒2型的相互作用
由最近出现的严重急性呼吸综合征冠状病毒2型(严重急性呼吸系统综合征冠状病毒冠状病毒2型)引起的冠状病毒疾病代表了一种重大的公共卫生,它使世界陷入了现代前所未有的危机。更好地了解先天免疫反应可能有助于抗击这一流行病,并为未来可能爆发的疫情做好更好的准备。有趣的是,先天免疫细胞可以产生一种称为训练免疫的非特异性记忆。这篇综述详细介绍了有关严重急性呼吸系统综合征冠状病毒2型与先天免疫细胞相互作用的最新证据,特别是那些已经证明具有训练免疫活性的细胞。
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