Positron Emission Tomography in Renal Cell Carcinoma

IF 0.1 Q4 ONCOLOGY Uroonkoloji Bulteni-Bulletin of Urooncology Pub Date : 2018-06-12 DOI:10.4274/UOB.946
Ç. Soydal, Y. Urun
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Abstract

Renal cell carcinoma (RCC) is the most common solid kidney tumor. Contrast-enhanced computed tomography (CT) is the most frequently used imaging modality in the diagnosis, staging, and evaluation of recurrence and treatment response in patients with RCC. The overall success rate of CT for these indications is reported to be between 61% and 91% (1,2,3). However, as RCCs may appear isodense, hypodense, or hyperdense, it is difficult to distinguish benign and malignant renal masses by morphological methods (4). Magnetic resonance imaging (MRI) is recommended in cases where CT is contraindicated, such as patients who have contrast allergy or are pregnant. However, MRI is no more accurate than CT. This increases the importance of positron emission tomography (PET), which enables metabolic evaluation in addition to visualizing anatomic changes. In this review, we discuss currently available literature data regarding the use of PET applications with different radiopharmaceuticals in patients with RCC. Applications of Positron Emission Tomography in Renal Cell Carcinoma
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肾细胞癌的正电子发射断层扫描
肾细胞癌(RCC)是最常见的肾脏实体瘤。在RCC患者的诊断、分期、复发和治疗反应评估中,CT是最常用的成像方式。据报道,CT对这些适应症的总体成功率在61%和91%之间(1,2,3)。然而,由于RCCs可能表现为等密度、低密度或高密度,因此很难通过形态学方法区分良性和恶性肾脏肿块(4)。在CT禁忌的情况下,如造影剂过敏或怀孕的患者,建议使用磁共振成像(MRI)。然而,MRI并不比CT更准确。这增加了正电子发射断层扫描(PET)的重要性,PET除了可以可视化解剖变化之外,还可以进行代谢评估。在这篇综述中,我们讨论了目前可用的关于PET与不同放射性药物在RCC患者中的应用的文献数据。正电子发射断层扫描在肾癌中的应用
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