Evaluating the environmental and therapeutic impacts of dietary supplement (Case study: The supplement Oyox for prevention of environment damages, treatment and disorders in the hepatobilliary system)

Q3 Agricultural and Biological Sciences caspian journal of environmental sciences Pub Date : 2021-07-01 DOI:10.22124/CJES.2021.4923
R. Roitman, W. Schatton, Evgeny Ilyich Maevsky
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Abstract

Globally recommended diets are a powerful method for raising the public's awareness of dietary choices. Although dietary choices drive both health and environmental outcomes, these diets make almost no reference to environmental impacts. Besides, Encephalic damage and disorders of the hepatobiliary system occur against the background of metabolic disorders. Metabolic processes largely depend on the activity and the qualitative and quantitative characteristics of sirtuin-type proteins. Protein deficiency can be filled by artificially introducing them into the body through dietary supplements. The study aimed to analyze the possibilities of using the dietary supplement OYOX to prevent environmental harm as well as treating encephalic damage and disorders of the hepatobiliary system. We used theoretical and practical research methods. In particular, the methods of analysis of literature sources, statistical data, results of clinical and preclinical studies were used. The method of generalization, analysis, systematization, classification of the obtained data was used. The results were evaluated 3 and 6 months after taking the dietary supplement. In the group of people taking OYOX, a statistically significant decrease was observed in the percentage of short telomeres (p = 0.029); a decrease in the percentage of senescent cytotoxic (CD8+ / CD28-) T cells (by 1.5%; 4.4%; 8.6% and 7.5% after 3 and 6 months respectively); improvement in lipid and carbohydrate metabolism glycosylated hemoglobin (HbA, 1%) by 4.9% (p = 0.01), total cholesterol 5.7 mmol  L-1 (p = 0.003), low density lipoprotein (LCL-C): 3.82 mmol  L-1 (p = 0.0021), homocysteine: 3.4 mmol L-1  (p = 0.001). In conclusions, dietary supplement OYOX is effectively used to eliminate the deficiency of sirtuin-type proteins SIR1, SIR3, SIR6.
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评估膳食补充剂对环境和治疗的影响(案例研究:补充剂Oyox用于预防环境损害、治疗肝胆系统疾病)
全球推荐饮食是提高公众对饮食选择意识的有力方法。尽管饮食选择会影响健康和环境,但这些饮食几乎没有提及环境影响。此外,脑损伤和肝胆系统紊乱是在代谢紊乱的背景下发生的。代谢过程在很大程度上取决于sirtuin型蛋白质的活性以及定性和定量特征。蛋白质缺乏可以通过膳食补充剂人工将其引入体内来填补。本研究旨在分析使用膳食补充剂OYOX预防环境危害以及治疗颅内损伤和肝胆系统疾病的可能性。我们采用了理论和实践相结合的研究方法。特别是,使用了文献来源、统计数据、临床和临床前研究结果的分析方法。对所获得的数据采用了归纳、分析、系统化、分类的方法。在服用膳食补充剂3个月和6个月后对结果进行评估。在服用OYOX的人群中,观察到短端粒的百分比在统计学上显著下降(p=0.029);衰老细胞毒性(CD8+/CD28-)T细胞的百分比降低(3个月和6个月后分别降低1.5%、4.4%、8.6%和7.5%);脂质和碳水化合物代谢改善糖化血红蛋白(HbA,1%)4.9%(p=0.01),总胆固醇5.7mmol L-1(p=0.003),低密度脂蛋白(LCL-C)3.82mmol L-1(p=0.0021),同型半胱氨酸3.4mmol L-1(p=0.001)。
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来源期刊
caspian journal of environmental sciences
caspian journal of environmental sciences Environmental Science-Environmental Science (all)
CiteScore
2.30
自引率
0.00%
发文量
0
审稿时长
5 weeks
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