Practice of linear quality control on manually compounded total nutrient admixtures

Zhang Jianzhong, Lao Donghui, Yao Bangxin, Jiang-hua Yi, Yang Chun, Wu Guohao, Lv Qianzhou
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Abstract

Objective To establish a quality control model ensuring good stability and compatibility of manually compounded total nutrient admixtures (TNA). Methods A parenteral nutrition medication order entry system was establish for standardizing nutritional medication usage and supporting physician's TNA prescribing. TNA medication orders were reviewed by pharmacists for validating the stability and compatibility. TNAs were compounded by pharmacists in a standard way following "four factors of sterile compounding" . The goal of quality control was achieved by establishment of the preliminary standard. Results The quality of manually compounded total nutrient admixtures achieved the goal since pharmacy intravenous admixture service (PIVAS) started on 2003. Conclusions The quality of TNA is well assured while manually compounded by pharmacists in PIVAS. Key words: Total nutrient admixtures; Pharmacist; Pharmacy intravenous admixture service
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人工配制全营养外加剂线性质量控制的实践
目的建立确保人工配制的全营养掺合料具有良好稳定性和相容性的质量控制模型。方法建立肠外营养医嘱录入系统,规范营养用药,支持医师开具TNA处方。药剂师对TNA医嘱进行审查,以验证其稳定性和兼容性。TNA由药剂师按照“无菌配制的四个因素”的标准方式配制。质量控制的目标是通过建立初步标准来实现的。结果自2003年开始提供静脉药物掺合剂服务以来,人工配制的全营养掺合剂的质量达到了预期目标。结论药剂师在PIVAS中手工配制TNA,可保证TNA的质量。关键词:全营养外加剂;药剂师;药房静脉混合用药服务
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来源期刊
中华临床营养杂志
中华临床营养杂志 Nursing-Nutrition and Dietetics
CiteScore
0.20
自引率
0.00%
发文量
2282
期刊介绍: The Chinese Journal of Clinical Nutrition was founded in 1993. It is the first professional academic journal (bimonthly) in my country co-sponsored by the Chinese Medical Association and the Chinese Academy of Medical Sciences to disseminate information on clinical nutrition support, nutrient metabolism, the impact of nutrition support on outcomes and "cost-effectiveness", as well as translational medicine and nutrition research. It is also a professional journal of the Chinese Medical Association's Parenteral and Enteral Nutrition Branch. The purpose of the Chinese Journal of Clinical Nutrition is to promote the rapid dissemination of knowledge on nutrient metabolism and the rational application of parenteral and enteral nutrition, focusing on the combination of multidisciplinary and multi-regional field investigations and clinical research. It mainly reports on nutritional risk screening related to the indications of parenteral and enteral nutrition support, "cost-effectiveness" research on nutritional drugs, consensus on clinical nutrition, guidelines, expert reviews, randomized controlled studies, cohort studies, glycoprotein and other nutrient metabolism research, systematic evaluation of clinical research, evidence-based case reports, special reviews, case reports and clinical experience exchanges, etc., and has a special column on new technologies related to the field of clinical nutrition and their clinical applications.
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