The potential role of zinc, magnesium and selenium against COVID-19: a pragmatic review

L. Pecoraro, Lucia Martini, Chiara Salvottini, L. Dalle Carbonare, G. Piacentini, A. Pietrobelli
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引用次数: 1

Abstract

ABSTRACT INTRODUCTION: Several studies have analyzed the role of antioxidant minerals as positive modulators of the immune system in facing viral infections. We discuss their possible protective role in Sars-Cov 2 infection selecting minerals for which literature provides most evidences, such as zinc (Zn), magnesium (Mg), and selenium (Se).DISCUSSION: All these minerals have a role in modulating antiviral and antibacterial immunity and to regulate the inflammatory response. Their deficiency is associated with a higher prevalence of respiratory tract infections andendothelial dysfunction. These features are related to COVID-19 pathophysiology.CONCLUSIONS: It seems that an optimal micronutrient status in terms of Zn, Mg and Se, is able to effectively strengthen the immune system during the COVID-19 infection. Anyway, further studies are necessary.
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锌、镁和硒对新冠肺炎的潜在作用:一项实用综述
摘要简介:一些研究分析了抗氧化矿物质作为免疫系统的积极调节剂在面对病毒感染时的作用。我们讨论了它们在严重急性呼吸系统综合征冠状病毒2型感染中可能的保护作用,选择了文献提供最多证据的矿物质,如锌(Zn)、镁(Mg)和硒(Se)。讨论:所有这些矿物质都在调节抗病毒和抗菌免疫以及调节炎症反应中发挥作用。它们的缺乏与呼吸道感染和内皮功能障碍的患病率较高有关。这些特征与新冠肺炎的病理生理学有关。结论:在新冠肺炎感染期间,锌、镁和硒的最佳微量营养素状态似乎能够有效增强免疫系统。无论如何,进一步的研究是必要的。
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