Analysis of Flap Failures in Microvascular Head and Neck Reconstructions: 11-Year Single-Center Results

Daria Jokinen, M. Kuuskeri, M. Helminen, M. Kääriäinen
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Abstract

Abstract Background  Free flap reconstruction is the gold standard in head and neck reconstructions. The current article analyzes failed free flaps in the head and neck region during an 11-year period in a single center aiming to discover factors that could be influenced in order to reduce the risk for flap failure. Methods  During the 11-year study period, 336 patients underwent free flap reconstruction at Tampere University Hospital, Tampere, Finland. The patients' average age was 62 years (range 14–92 years). Note that 201 (61.5%) of the patients were women and 135 (38.5%) men. Medical records were reviewed for demographics, comorbidities, neoadjuvant and adjuvant therapies, free flap type, area of reconstruction, and intraoperative and postoperative complications. Statistical analyses were performed. Results  Ten (3%) of the 336 free flaps failed. Patients' age, comorbidities, smoking, dosage of anticoagulation, free flap type, or the location of the defect did not influence the risk of flap failure. All lost flaps were postoperatively followed by clinical monitoring only. In contrast, 89% of all flaps had both Licox (Integra LifeSciences Corp, NJ) and clinical follow-up postoperatively. In six (60%) of the failed cases, a second free flap surgery was performed as a salvage procedure, with a survival rate of 83.3%. Conclusion  Our free flap success rate of 97% is in accordance with that of other centers that perform head and neck reconstructions. According to our findings, free flap reconstructions can be successfully performed on elderly patients and patients with comorbidities. Smoking did not increase the flap loss rate. We encourage the use of other methods in addition to clinical monitoring to follow the flaps after head and neck free flap reconstructions. All flap types used have high success rates, and reconstruction can be conducted with the most suitable flaps for the demands of the defect.
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头颈部微血管重建中皮瓣失效的11年单中心结果分析
摘要背景 游离皮瓣重建是头颈部重建的黄金标准。本文分析了一个中心11年来头颈部游离皮瓣失效的情况,旨在发现可能受到影响的因素,以降低皮瓣失效的风险。方法 在11年的研究期间,336名患者在芬兰坦佩雷的坦佩雷大学医院接受了游离皮瓣重建。患者的平均年龄为62岁(14-92岁)。注意,201名(61.5%)患者为女性,135名(38.5%)为男性。对医疗记录进行了回顾,包括人口统计学、合并症、新辅助和辅助治疗、游离皮瓣类型、重建面积以及术中和术后并发症。进行了统计分析。后果 336个自由皮瓣中有10个(3%)失败。患者的年龄、合并症、吸烟、抗凝剂量、游离皮瓣类型或缺损位置不会影响皮瓣失败的风险。所有丢失的皮瓣均在术后仅进行临床监测。相反,89%的皮瓣同时进行了Licox(Integra LifeSciences Corp,NJ)和术后临床随访。在6例(60%)失败的病例中,进行了第二次游离皮瓣手术作为挽救手术,存活率为83.3% 我们97%的游离皮瓣成功率与其他进行头颈部重建的中心一致。根据我们的研究结果,老年患者和合并症患者可以成功地进行游离皮瓣重建。吸烟不会增加皮瓣脱落率。除了临床监测外,我们鼓励使用其他方法来跟踪头颈部游离皮瓣重建后的皮瓣。使用的所有类型的皮瓣都有很高的成功率,并且可以使用最适合缺损需求的皮瓣进行重建。
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