{"title":"T1 relaxation time in the evaluation of liver fibrosis; with native MR relaxometry","authors":"Firathan Sarialtin, H. Yiğit, E. Ergun, P. Koşar","doi":"10.5472/marumj.1302518","DOIUrl":null,"url":null,"abstract":"Objective: Non-invasive methods have been investigated as an alternative to biopsy in assessing liver fibrosis. This study aimed to \nevaluate the relationship between liver T1 relaxation time and liver fibrosis as a non-invasive alternative method. \nPatients and Methods: This study analyzed 1.5T magnetic resonance (MR) images of 86 patients retrospectively. The participants were \ndivided into two groups: patients with chronic hepatitis and the control group. Native variable flip angle (VFA) T1 mapping technique \nwas used to estimate liver T1 relaxation time. T1 mapping sequence, T2* mapping sequence, and image analysis were performed. The \nliver size, the spleen size, the liver T1 relaxation time, and the liver T2* relaxation time were recorded. \nResults: The T1 relaxation time was 758.4 ± 121.1 ms in the chronic hepatitis group and 600.2 ± 67 ms in the control group. The T1 \nrelaxation time of the patient group was significantly higher than that of the control group (p","PeriodicalId":43341,"journal":{"name":"Marmara Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Marmara Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5472/marumj.1302518","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Non-invasive methods have been investigated as an alternative to biopsy in assessing liver fibrosis. This study aimed to
evaluate the relationship between liver T1 relaxation time and liver fibrosis as a non-invasive alternative method.
Patients and Methods: This study analyzed 1.5T magnetic resonance (MR) images of 86 patients retrospectively. The participants were
divided into two groups: patients with chronic hepatitis and the control group. Native variable flip angle (VFA) T1 mapping technique
was used to estimate liver T1 relaxation time. T1 mapping sequence, T2* mapping sequence, and image analysis were performed. The
liver size, the spleen size, the liver T1 relaxation time, and the liver T2* relaxation time were recorded.
Results: The T1 relaxation time was 758.4 ± 121.1 ms in the chronic hepatitis group and 600.2 ± 67 ms in the control group. The T1
relaxation time of the patient group was significantly higher than that of the control group (p
期刊介绍：
Marmara Medical Journal, Marmara Üniversitesi Tıp Fakültesi tarafından yılda üç kere yayımlanan multidisipliner bir dergidir. Bu dergide tıbbın tüm alanlarına ait orijinal araştırma makaleleri, olgu sunumları ve derlemeler İngilizce veya Türkçe olarak yer alır.
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