Rapid Reduction of HbA1c and Weight in Elderly Patient with Type 2 Diabetes (T2D) And Depression by Oral Semaglutide (Rybelsus)

H. Bando, Kenji Hayashi, Kyoko Sumitomo, Kazuya Miki, Asami Kamoto
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引用次数: 4

Abstract

Background: Oral semaglutide (Rybelsus) has been in focus for type 2 diabetes (T2D). Case Presentation: The patient is a 73-year-old male with T2D treated with metformin, Ipragliflozin, and rosuvastatin. He was diagnosed with depression by the Geriatric depression scale (GDS) with a stable condition by mirtazapine. His diabetic control was exacerbated to HbA1c 8.8% and weight 63.5kg in Feb 2022. Results: He started to take Rybelsus, and then clinical improvement was found as HbA1c 6.9% and weight 57.5kg for 4 months. Discussion: Remarkable effect of HbA1c and weight may be from longer fasting time after post-med, and regular lifestyle from the stable psychosomatic situation.
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口服Semagulide(Rybelsus)快速降低老年2型糖尿病(T2D)和抑郁症患者的HbA1c和体重
背景:口服赛马鲁肽(Rybelsus)一直是2型糖尿病(T2D)的焦点。病例介绍:患者为一名73岁的男性,患有T2D,接受二甲双胍、依匹拉利嗪和瑞舒伐他汀治疗。他被老年抑郁症量表(GDS)诊断为抑郁症,服用米氮平病情稳定。2022年2月,他的糖尿病控制恶化至HbA1c 8.8%,体重63.5kg。结果:他开始服用Rybelsus,随后临床改善为HbA1c 6.9%,体重57.5kg,持续4个月。讨论:HbA1c和体重的显著影响可能来自于服药后较长的禁食时间,以及稳定的身心状况带来的规律的生活方式。
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