Numerical analysis of integrated photonics structures for hemoglobin sensor application

IF 0.5 Q4 OPTICS Photonics Letters of Poland Pub Date : 2020-07-01 DOI:10.4302/plp.v12i2.1008
P. Struk
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Abstract

This paper presents sensor structure dedicated for determination the key properties of blood – concentration level and oxidation level. The sensor structure is based integrated optics circuit with diamond-based planar waveguide including prism and grating coupler. The paper is focused on numerical analysis of selected properties of sensor structure for optimization sensing parameters. Full Text: PDF References D.A. Gell, Blood Cells, "Structure and function of haemoglobins", Molecules and Diseases 70 (2018). CrossRef I. Singh, A. Weston, A. Kundur, G. Dobie, Haematology Case Studies with Blood Cell Morphology and Pathophysiology (Elsevier: Amsterdam, The Netherlands, 2017) DirectLink P. D. Sturkie, P. Griminger, Blood: Physical Characteristics, Formed Elements, Hemoglobin, and Coagulation Avian Physiology (Springer-Verlag New York Inc. 1976). CrossRef A. Dutta, B. Deka, P.P. Partha, Planar Waveguide Optical Sensors: From Theory to Applications (Springer: Berlin, Germany, 2016). CrossRef S. Kang, K. Sasaki, H. Minamitani, "Determining the absorption coefficient of hemoglobin derivatives with integrated optic waveguide sensor", IEEE Engineering in Medicine and Biology Society (1992). CrossRef P. Struk, "Design of an Integrated Optics Sensor Structure Based on Diamond Waveguide for Hemoglobin Property Detection", Materials 12(1) 175 (2019). CrossRef W. Lukosz, K. Tiefenthaler, "Sensitivity of integrated optical grating and prism couplers as (bio)chemical sensors", Sensors and Actuators 15 (1988). CrossRef P.V. Lambeck, "Integrated optical sensors for the chemical domain", Measurement Science and Technology - IOPscience 17 (2006), CrossRef W. Lukosz, "Integrated optical chemical and direct biochemical sensors", Sensors and Actuators B: Chemical 29 (1995). CrossRef P. Struk, T. Pustelny, K. Golaszewska, E. Kaminska, M. Borysiewicz, M. Ekielski, And A. Piotrowska, "Photonic structures with grating couplers based on ZnO", Opto−Electronics Review 19(4) (2011). CrossRef J. Haas, E. V. Catalan, P. Piron, F. Nikolajeff, L. Osterlund, M. Karlsson, B. Mizaikoff, "Polycrystalline Diamond Thin-Film Waveguides for Mid-Infrared Evanescent Field Sensors", ACS Omega 3 (2018). CrossRef P. Struk, "Design of an integrated optics sensor structure for hemoglobin property detection", Proceedings of SPIE 11204 (2019). CrossRef P. Struk, T. Pustelny, K. Golaszewska, E. Kaminska, M. Borysiewicz, M. Ekielski, A. Piotrowska, "Hybrid photonics structures with grating and prism couplers based on ZnO waveguides", Opto-Electronics Review 21 (2013). CrossRef V. Prajzler, M. Varga, P. Nekvindova, Z.; Remes, A. Kromka, "Design and investigation of properties of nanocrystalline diamond optical planar waveguides", Optics Express 21 (2013), CrossRef E.N. Lazareva, V.V. Tuchin, "Measurement of refractive index of hemoglobin in the visible/NIR spectral range", Journal of Biomedical Optics 23 (2018). CrossRef Optiwave Systems Inc. "OptiFDTD Technical Background and Tutorials - Finite" (2013). DirectLink K. Yee, Antennas and Propagation, "Numerical solution of initial boundary value problems involving maxwell's equations in isotropic media", IEEE Transactions 14,3 (1966). CrossRef
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血红蛋白传感器应用集成光子学结构的数值分析
本文介绍了一种用于测定血液浓度水平和氧化水平关键特性的传感器结构。传感器结构是基于集成光学电路的,该电路具有基于金刚石的平面波导,包括棱镜和光栅耦合器。本文的重点是对传感器结构的选定特性进行数值分析,以优化传感参数。全文:PDF参考文献D.A.Gell,血细胞,“血红蛋白的结构和功能”,分子和疾病70(2018)。CrossRef I.Singh,A.Weston,A.Kundur,G.Dobie,《血细胞形态学和病理生理学案例研究》(爱思唯尔:荷兰阿姆斯特丹,2017)DirectLink P.D.Sturkie,P.Griminger,《血液:物理特征、形成元素、血红蛋白和凝血鸟类生理学》(Springer-Verlag New York股份有限公司1976)。CrossRef A.Dutta,B.Deka,P.P.Partha,平面波导光学传感器:从理论到应用(施普林格:德国柏林,2016)。CrossRef S.Kang,K.Sasaki,H.Minamitani,“用集成光波导传感器测定血红蛋白衍生物的吸收系数”,IEEE医学与生物学会工程(1992)。CrossRef P.Struk,“用于血红蛋白特性检测的基于金刚石波导的集成光学传感器结构的设计”,材料12(1)175(2019)。CrossRef W.Lukosz,K.Tiefenthaler,“集成光栅和棱镜耦合器作为(生物)化学传感器的灵敏度”,传感器和致动器15(1988)。CrossRef P.V.Lambeck,“化学领域的集成光学传感器”,测量科学与技术-IOPscience 17(2006),CrossRef W.Lukosz,“集成光学化学和直接生化传感器”,传感器和执行器B:chemical 29(1995)。CrossRef P.Struk、T.Pustelny、K.Golaszewska、E.Kaminska、M.Borysiewicz、M.Ekielski和A.Piotrowska,“基于ZnO的光栅耦合器光子结构”,光电子评论19(4)(2011)。CrossRef J.Haas,E.V.Catalan,P.Piron,F.Nikolajeff,L.Osterlund,M.Karlsson,B.Mizaikoff,“用于中红外倏逝场传感器的聚晶金刚石薄膜波导”,ACS Omega 3(2018)。CrossRef P.Struk,“用于血红蛋白特性检测的集成光学传感器结构的设计”,《SPIE论文集》11204(2019)。CrossRef P.Struk,T.Pustelny,K.Golaszewska,E.Kaminska,M.Borysiewicz,M.Ekielski,A.Piotrowska,“基于ZnO波导的光栅和棱镜耦合器的混合光子学结构”,《光电子评论》第21期(2013)。CrossRef V.Prajzler,M.Varga,P.Nekvindova,Z。;Remes,A.Kromka,“纳米晶体金刚石光学平面波导的设计和性能研究”,Optics Express 21(2013),CrossRef E.N.Lazareva,V.V.Tuchin,“可见光/近红外光谱范围内血红蛋白折射率的测量”,《生物医学光学杂志》23(2018)。CrossRef Optiwave Systems股份有限公司“OptiFDTD技术背景和教程-有限”(2013)。DirectLink K.Yee,天线和传播,“各向同性介质中涉及麦克斯韦方程的初边值问题的数值解”,IEEE汇刊14,3(1966)。CrossRef
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24
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