Receptor Pharmacology and Other Relevant Factors in Lower Urinary Tract Pathology under a Functional and Toxicological Approach: Instrument to Better Manage Antimicrobials Therapy

Abstract

This work is produced under a pharmaceuticalpharmacological, patho-physiological and toxicological point of view and it focused on male individuals and not under a surgery light. Various receptors control the LUT like cholinergic, alpha adrenergic, nociceptors, PDE5, androgen and other are involved in physio-pathology of this condition (Figures 1-14). Cholinergic, adrenergic innervation in bladder and bladder neck, adrenergic in prostate, androgen receptor, PDE5 rec, nociceptors but also other system