Pub Date : 2021-08-27DOI: 10.29328/JOURNAL.APCR.1001023
A. Nagy, C. Sergi, J. D. Nanassy, Lesleigh S Abbot, A. Arnoldo, C. Hawkins, B. Ngan
We report a case of a right gluteal mass from the sacroiliac joint to the knee of an infant girl. Biopsy showed histopathological features similar to infantile fi brosarcoma (IFS). However, unlike most IFS, no ETV6-NTRK3 fusion gene abnormality was detected. Molecular analysis with TruSight RNA Pan-Cancer Panel detected the presence of KIAA1549-BRAF translocation and an oncogenic NF2p.Q459* SNV with potential clinical signifi cance. A review revealed that the combination of this patient’s tumor site with the presence of a KIAA1549-BRAF translocation abnormality and an accompanying single nucleotide variant has not been previously described. The detection of this translocation abnormality raises the possibility that the spindle cell tumors in infants with an absence of the ETV6-NTRK3 fusion gene abnormality might have a distinct pathogenetic mechanism diff erent from the previously known IFS and congenital mesoblastic nephroma. Furthermore, the discovery of BRAF translocation and its aberrant signaling of the mitogen-activated protein kinase (MAPK) pathway in this tumor contributes to the promise of clinical benefi t of using the MEKi trametinib for the treatment of progressive disease that is refractory to conventional chemotherapy.
{"title":"A novel case of an infantile fibrosarcoma-like tumor with KIAA1549 - BRAF translocation and an oncogenic NF2 p.Q459* SNV with potential clinical significance","authors":"A. Nagy, C. Sergi, J. D. Nanassy, Lesleigh S Abbot, A. Arnoldo, C. Hawkins, B. Ngan","doi":"10.29328/JOURNAL.APCR.1001023","DOIUrl":"https://doi.org/10.29328/JOURNAL.APCR.1001023","url":null,"abstract":"We report a case of a right gluteal mass from the sacroiliac joint to the knee of an infant girl. Biopsy showed histopathological features similar to infantile fi brosarcoma (IFS). However, unlike most IFS, no ETV6-NTRK3 fusion gene abnormality was detected. Molecular analysis with TruSight RNA Pan-Cancer Panel detected the presence of KIAA1549-BRAF translocation and an oncogenic NF2p.Q459* SNV with potential clinical signifi cance. A review revealed that the combination of this patient’s tumor site with the presence of a KIAA1549-BRAF translocation abnormality and an accompanying single nucleotide variant has not been previously described. The detection of this translocation abnormality raises the possibility that the spindle cell tumors in infants with an absence of the ETV6-NTRK3 fusion gene abnormality might have a distinct pathogenetic mechanism diff erent from the previously known IFS and congenital mesoblastic nephroma. Furthermore, the discovery of BRAF translocation and its aberrant signaling of the mitogen-activated protein kinase (MAPK) pathway in this tumor contributes to the promise of clinical benefi t of using the MEKi trametinib for the treatment of progressive disease that is refractory to conventional chemotherapy.","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"365 1","pages":"016-019"},"PeriodicalIF":0.0,"publicationDate":"2021-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41284032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-15DOI: 10.29328/JOURNAL.APCR.1001021
Ohara Tadashi
Currently, the emergence of highly virulent mutants in Europe and the United States has caused refractory recurrent Clostridium diffi cile infection (RCDI) to be a problem in clinical practice. In 2013, the Netherland group demonstrated breakthrough therapeutic effi cacy in fecal microbial transplant (FMT) treatment clinical trials for RCDI, and FMT treatment is rapidly gaining attention. In addition to RCDI, FMT treatment has been attempted in various gastrointestinal diseases such as infl ammatory bowel disease, irritable bowel syndrome and chronic constipation, as well as extragastrointestinal diseases. In this review, I would like to describe the current status, complications and prospects of FMT treatment. Review Article
{"title":"Current status, complications and prospects of fecal microbiota transplantation therapy","authors":"Ohara Tadashi","doi":"10.29328/JOURNAL.APCR.1001021","DOIUrl":"https://doi.org/10.29328/JOURNAL.APCR.1001021","url":null,"abstract":"Currently, the emergence of highly virulent mutants in Europe and the United States has caused refractory recurrent Clostridium diffi cile infection (RCDI) to be a problem in clinical practice. In 2013, the Netherland group demonstrated breakthrough therapeutic effi cacy in fecal microbial transplant (FMT) treatment clinical trials for RCDI, and FMT treatment is rapidly gaining attention. In addition to RCDI, FMT treatment has been attempted in various gastrointestinal diseases such as infl ammatory bowel disease, irritable bowel syndrome and chronic constipation, as well as extragastrointestinal diseases. In this review, I would like to describe the current status, complications and prospects of FMT treatment. Review Article","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"5 1","pages":"004-009"},"PeriodicalIF":0.0,"publicationDate":"2021-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44449441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-30DOI: 10.29328/JOURNAL.APCR.1001019
B. Lenjani, N. Baftiu, P. Rashiti, Gani Shabani, B. Krasniqi, Arber Demiri, Besarta Pelaj, Fllanza Spahiu, A. Demi, Dardan Lenjani
Emergency medical care in palliative patients during the COVID-19 pandemic, it is important to provide a consistent treatment for stable patients that should be consistent with the goals and benefi ts, the perspective of these patients, but avoiding palliative patients with a poor prognosis that is unlikely to survive. Cancer is the second leading cause of death in the world around 8.8 million deaths a year. Worldwide, about 7-10 million patients are diagnosed with cancer each year, recently there has been a signifi cant increase in the number of cases diagnosed with cancer. About 70% of cancer deaths are in lowand middle-income countries. The goals of emergency medical care based on the criteria of BLS and ACLS, that is should be done “Do not do resuscitation, do not intubate but continue medical treatment excluding endotracheal intubation without prospects for the patient, but off ering BLS only treatment concentrated symptomatic. ED is often the only place that can provide the necessary medical interventions (e.g., intravenous fl uids or pain management medications. Medications as well as immediate access to advanced diagnostic tests when needed such as CT, RM and other diagnostic and treatment procedures. Research Article
{"title":"Emergency care sick palliative and problems oncology in emergency department during the COVID-19 pandemic","authors":"B. Lenjani, N. Baftiu, P. Rashiti, Gani Shabani, B. Krasniqi, Arber Demiri, Besarta Pelaj, Fllanza Spahiu, A. Demi, Dardan Lenjani","doi":"10.29328/JOURNAL.APCR.1001019","DOIUrl":"https://doi.org/10.29328/JOURNAL.APCR.1001019","url":null,"abstract":"Emergency medical care in palliative patients during the COVID-19 pandemic, it is important to provide a consistent treatment for stable patients that should be consistent with the goals and benefi ts, the perspective of these patients, but avoiding palliative patients with a poor prognosis that is unlikely to survive. Cancer is the second leading cause of death in the world around 8.8 million deaths a year. Worldwide, about 7-10 million patients are diagnosed with cancer each year, recently there has been a signifi cant increase in the number of cases diagnosed with cancer. About 70% of cancer deaths are in lowand middle-income countries. The goals of emergency medical care based on the criteria of BLS and ACLS, that is should be done “Do not do resuscitation, do not intubate but continue medical treatment excluding endotracheal intubation without prospects for the patient, but off ering BLS only treatment concentrated symptomatic. ED is often the only place that can provide the necessary medical interventions (e.g., intravenous fl uids or pain management medications. Medications as well as immediate access to advanced diagnostic tests when needed such as CT, RM and other diagnostic and treatment procedures. Research Article","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"4 1","pages":"024-027"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46044650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-24DOI: 10.29328/journal.apcr.1001017
Farah Qudsia, Muhammad Rehan, S. Riaz
Typhoid fever is a systemic infection caused by Salmonella enterica serotype typhi. It is of major concern in tropical regions of the world. Highest episodes of typhoid fever occur in Asia i.e.93%. Early diagnosis of the disease is mandatory to lower the mortality rate associated with it as well as to prevent the emergence of antimicrobial drug resistance by Salmonella typhi. Research work was conducted in Immunology Department of the Children’s Hospital, Lahore for the period of one year including a total of 60 patients suspected of having typhoid fever. Serum samples of these patients were tested for Typhidot IgG and IgM antibodies as well as for the antibodies against TO and TH antigens using Widal test. Of the total 60 patients, 10 (16.7%) were positive for both Typhidot IgG and IgM, 16 (26.7%) were positive for Typhidot IgM, 3 (5%) were Positive for Typhidot IgG and 31 (51.66%) were negative for both Typhidot IgG and IgM. Reading the results of Widal test, 8 (13.33%) were positive for Widal TO and TH antigens, 3 (5%) were positive for Widal TO antigen, 19 (31.7%) were positive for Widal TH antigen and 30 (50%) were negative for Widal TO and TH antigens. IgM is positive at the early stage of acute typhoid fever, IgM along with IgG positive means the middle stage of acute illness. The detection of only IgG cannot discriminate between acute and convalescent phases as it can stay in the serum for at least 2 years or more. The Typhidot test is much helpful for the rapid diagnosis of typhoid fever as compared to Widal test which is still being used in some set ups in poor countries, although has become mostly obsolete. By testing the rise of IgM and IgG antibodies against Salmonella typhi, we can detect the infection at early and late stages, respectively. Research Article
{"title":"Molecular analysis of immunoglobulins related to salmonella typhi in pediatric patients","authors":"Farah Qudsia, Muhammad Rehan, S. Riaz","doi":"10.29328/journal.apcr.1001017","DOIUrl":"https://doi.org/10.29328/journal.apcr.1001017","url":null,"abstract":"Typhoid fever is a systemic infection caused by Salmonella enterica serotype typhi. It is of major concern in tropical regions of the world. Highest episodes of typhoid fever occur in Asia i.e.93%. Early diagnosis of the disease is mandatory to lower the mortality rate associated with it as well as to prevent the emergence of antimicrobial drug resistance by Salmonella typhi. Research work was conducted in Immunology Department of the Children’s Hospital, Lahore for the period of one year including a total of 60 patients suspected of having typhoid fever. Serum samples of these patients were tested for Typhidot IgG and IgM antibodies as well as for the antibodies against TO and TH antigens using Widal test. Of the total 60 patients, 10 (16.7%) were positive for both Typhidot IgG and IgM, 16 (26.7%) were positive for Typhidot IgM, 3 (5%) were Positive for Typhidot IgG and 31 (51.66%) were negative for both Typhidot IgG and IgM. Reading the results of Widal test, 8 (13.33%) were positive for Widal TO and TH antigens, 3 (5%) were positive for Widal TO antigen, 19 (31.7%) were positive for Widal TH antigen and 30 (50%) were negative for Widal TO and TH antigens. IgM is positive at the early stage of acute typhoid fever, IgM along with IgG positive means the middle stage of acute illness. The detection of only IgG cannot discriminate between acute and convalescent phases as it can stay in the serum for at least 2 years or more. The Typhidot test is much helpful for the rapid diagnosis of typhoid fever as compared to Widal test which is still being used in some set ups in poor countries, although has become mostly obsolete. By testing the rise of IgM and IgG antibodies against Salmonella typhi, we can detect the infection at early and late stages, respectively. Research Article","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"4 1","pages":"005-010"},"PeriodicalIF":0.0,"publicationDate":"2020-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49199887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study of the similarities and differences between different living organisms of the process by which normal cells are transformed into cancer cells.
研究正常细胞转化为癌症细胞过程中不同生物体之间的相似性和差异性。
{"title":"Comparative carcinogenesis.","authors":"S. Rogers","doi":"10.32388/55irnb","DOIUrl":"https://doi.org/10.32388/55irnb","url":null,"abstract":"The study of the similarities and differences between different living organisms of the process by which normal cells are transformed into cancer cells.","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"70 1","pages":"661-74"},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41891534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-14DOI: 10.29328/journal.apcr.1001016
C. Lombard
Uterine sections from 6 patients with incidental nodal lymphangioleiomyomatosis (LAM) were examined for LAM lesions by screening these sections with cathepsin K immunohistochemistry (IHC) stains. The hysterectomy specimens were all concurrent with the lymph node dissections in which the nodal LAM was discovered. In 4 of 6 patients microscopic lesions of pre-LAM were identifi ed and confi rmed by IHC staining for HMB-45 and beta-catenin. All lesions were grossly inapparent and also inapparent by routine hematoxylin and eosin stains. Three variants of pre-LAM lesions were identifi ed. None of the pre-LAM lesions had an associated lymphatic proliferation. It is proposed that these pre-LAM lesions gave rise to the incidental nodal LAM lesions. Furthermore, it is suggested that the absence of an associated lymphatic proliferation associated with these lesions may be a factor in the attenuated potential for spread and the only rare association of these nodal lesions with pulmonary LAM. Research Article
{"title":"Uterine precursor lesions in patients with incidental nodal lymphangioleiomyomatosis: A report of 4 cases","authors":"C. Lombard","doi":"10.29328/journal.apcr.1001016","DOIUrl":"https://doi.org/10.29328/journal.apcr.1001016","url":null,"abstract":"Uterine sections from 6 patients with incidental nodal lymphangioleiomyomatosis (LAM) were examined for LAM lesions by screening these sections with cathepsin K immunohistochemistry (IHC) stains. The hysterectomy specimens were all concurrent with the lymph node dissections in which the nodal LAM was discovered. In 4 of 6 patients microscopic lesions of pre-LAM were identifi ed and confi rmed by IHC staining for HMB-45 and beta-catenin. All lesions were grossly inapparent and also inapparent by routine hematoxylin and eosin stains. Three variants of pre-LAM lesions were identifi ed. None of the pre-LAM lesions had an associated lymphatic proliferation. It is proposed that these pre-LAM lesions gave rise to the incidental nodal LAM lesions. Furthermore, it is suggested that the absence of an associated lymphatic proliferation associated with these lesions may be a factor in the attenuated potential for spread and the only rare association of these nodal lesions with pulmonary LAM. Research Article","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"4 1","pages":"001-004"},"PeriodicalIF":0.0,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49110605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Results: The prevalence of childbirth among 40 years old and over was 0.61%. They were multiparous and large multiparous in 88% of the cases. The analysis showed that parturients aged 40 years and older were at signifi cant risk for caesarean section, with three times the risk of emergency caesarean section. The frequency of this emergency caesarean section increased with parity (RR = 3.04 [2.15-4.30], p = 10-10). Among their neonates, 23.42% were hypotrophic, 22.86% premature, 12% asphyxiated at birth, 13.14% admitted to neonatal resuscitation and 5.71% died in utero, but without signifi cant difference with the group unexposed. Perinatal death was 7.43% in women aged 40 and over vs 4% in 20 to 35 year olds (RR = 1.85 [0,89-3,86]; p = 0.052).
{"title":"Pregnancy and childbirth in women aged 40 and over at befelatanana maternity, Madagascar","authors":"Rakotomalala Nivoarimelina Zoly, Rakotozanany Besaina, Razafindraibe Andriatompoina Felanarivo, Ramarokoto Malalafinaritra Patrick Marco, Rafamatanantsoa Jean Florent, Kapche Wato Edith, Randriambololona Domoina Malala Aurelia","doi":"10.29328/journal.apcr.1001015","DOIUrl":"https://doi.org/10.29328/journal.apcr.1001015","url":null,"abstract":"Results: The prevalence of childbirth among 40 years old and over was 0.61%. They were multiparous and large multiparous in 88% of the cases. The analysis showed that parturients aged 40 years and older were at signifi cant risk for caesarean section, with three times the risk of emergency caesarean section. The frequency of this emergency caesarean section increased with parity (RR = 3.04 [2.15-4.30], p = 10-10). Among their neonates, 23.42% were hypotrophic, 22.86% premature, 12% asphyxiated at birth, 13.14% admitted to neonatal resuscitation and 5.71% died in utero, but without signifi cant difference with the group unexposed. Perinatal death was 7.43% in women aged 40 and over vs 4% in 20 to 35 year olds (RR = 1.85 [0,89-3,86]; p = 0.052).","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"3 1","pages":"022-027"},"PeriodicalIF":0.0,"publicationDate":"2019-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48148137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-03DOI: 10.29328/journal.apcr.1001014
Osmani* Freshteh
{"title":"Effect evaluation of vitamin D level amongst patients with chronic hepatitis B","authors":"Osmani* Freshteh","doi":"10.29328/journal.apcr.1001014","DOIUrl":"https://doi.org/10.29328/journal.apcr.1001014","url":null,"abstract":"","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"3 1","pages":"020-021"},"PeriodicalIF":0.0,"publicationDate":"2019-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45965534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-14DOI: 10.29328/JOURNAL.APCR.1001010
M. Luisetto
This work is produced under a pharmaceuticalpharmacological, patho-physiological and toxicological point of view and it focused on male individuals and not under a surgery light. Various receptors control the LUT like cholinergic, alpha adrenergic, nociceptors, PDE5, androgen and other are involved in physio-pathology of this condition (Figures 1-14). Cholinergic, adrenergic innervation in bladder and bladder neck, adrenergic in prostate, androgen receptor, PDE5 rec, nociceptors but also other system
{"title":"Receptor Pharmacology and Other Relevant Factors in Lower Urinary Tract Pathology under a Functional and Toxicological Approach: Instrument to Better Manage Antimicrobials Therapy","authors":"M. Luisetto","doi":"10.29328/JOURNAL.APCR.1001010","DOIUrl":"https://doi.org/10.29328/JOURNAL.APCR.1001010","url":null,"abstract":"This work is produced under a pharmaceuticalpharmacological, patho-physiological and toxicological point of view and it focused on male individuals and not under a surgery light. Various receptors control the LUT like cholinergic, alpha adrenergic, nociceptors, PDE5, androgen and other are involved in physio-pathology of this condition (Figures 1-14). Cholinergic, adrenergic innervation in bladder and bladder neck, adrenergic in prostate, androgen receptor, PDE5 rec, nociceptors but also other system","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"2 1","pages":"049-093"},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49413683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-05DOI: 10.29328/journal.apcr.1001009
L. Mauro
ALS is a chronic progressive neurodegenerative pathology involving motoneuron system (I and II, central and periferic or upper and lower motoneuron) with heavy symptomatology with progressive paralisys of voluntary muscle and since exitus. Different form: primary, familiar 5-10%, et other involving young, adults,ereditary, sporadic, acquired. In example see West Pacific foci, mutation SOD1 geography diffusion, sports related cases.
{"title":"Amyotropyc Lateral Sclerosis and Endogenous -Esogenous Toxicological Movens: New model to verify other Pharmacological Strategies","authors":"L. Mauro","doi":"10.29328/journal.apcr.1001009","DOIUrl":"https://doi.org/10.29328/journal.apcr.1001009","url":null,"abstract":"ALS is a chronic progressive neurodegenerative pathology involving motoneuron system (I and II, central and periferic or upper and lower motoneuron) with heavy symptomatology with progressive paralisys of voluntary muscle and since exitus. Different form: primary, familiar 5-10%, et other involving young, adults,ereditary, sporadic, acquired. In example see West Pacific foci, mutation SOD1 geography diffusion, sports related cases.","PeriodicalId":8289,"journal":{"name":"Archives of pathology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69930862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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