EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1)

L. Cristiano
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Abstract

Eukaryotic translation elongation factor 1 epsilon 1, alias EEF1E1, is a protein-coding gene that plays a role in the elongation step of translation. In particular, it is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex (MARS). Its expression is found frequently altered in human cancer cells and it is considered a putative tumor suppressor gene. This review collects the data on DNA/RNA, the protein encoded and the diseases where EEF1E1 is involved.
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EEF1E1(真核翻译延伸因子1ε1)
真核翻译延伸因子1ε1,别名EEF1E1,是一种蛋白质编码基因,在翻译的延伸步骤中发挥作用。特别地,它是大分子氨酰基tRNA合成酶复合物(MARS)的辅助成分。它在人类癌症细胞中的表达经常发生改变,被认为是公认的肿瘤抑制基因。这篇综述收集了有关DNA/RNA、编码的蛋白质以及EEF1E1所涉及的疾病的数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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