Numerical Modelling for the Droplets Formation in Microfluidics - A Review

IF 1.3 4区 工程技术 Q2 ENGINEERING, AEROSPACE Microgravity Science and Technology Pub Date : 2023-05-16 DOI:10.1007/s12217-023-10053-0
Liangyu Wu, Jian Qian, Xuyun Liu, Suchen Wu, Cheng Yu, Xiangdong Liu
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Abstract

Microfluidic technology has advantages in producing high-quality droplets with monodispersity which is promising in chemical engineering, biological medicine and so on. An in-depth study on the underlying mechanism of droplet formation in microfluidics is of great significance, and to understand it, numerical simulation is highly beneficial. This article reviews the substantial numerical methods used to study the fluid dynamics in microfluidic droplet formation, mainly including the continuum methods and mesoscale methods. Moreover, the principles of various methods and their applications in droplets formation in microfluidics have been thoroughly discussed, establishing the guidelines to further promote the numerical research in microfluidic droplet formation. The potential directions of numerical modelling for droplet formation in microfluidics are also given.

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微流体中液滴形成的数值模拟研究进展
微流控技术在制备高质量单分散液滴方面具有优势,在化工、生物医药等领域具有广阔的应用前景。深入研究微流体中液滴形成的潜在机理具有重要意义,而数值模拟对理解微流体中液滴形成的机理具有重要的借鉴意义。本文综述了用于研究微流体液滴形成流体动力学的大量数值方法,主要包括连续介质方法和中尺度方法。深入讨论了各种方法在微流控液滴形成中的原理及其应用,为进一步推进微流控液滴形成的数值研究奠定了指导。最后给出了微流体中液滴形成数值模拟的可能方向。
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来源期刊
Microgravity Science and Technology
Microgravity Science and Technology 工程技术-工程:宇航
CiteScore
3.50
自引率
44.40%
发文量
96
期刊介绍: Microgravity Science and Technology – An International Journal for Microgravity and Space Exploration Related Research is a is a peer-reviewed scientific journal concerned with all topics, experimental as well as theoretical, related to research carried out under conditions of altered gravity. Microgravity Science and Technology publishes papers dealing with studies performed on and prepared for platforms that provide real microgravity conditions (such as drop towers, parabolic flights, sounding rockets, reentry capsules and orbiting platforms), and on ground-based facilities aiming to simulate microgravity conditions on earth (such as levitrons, clinostats, random positioning machines, bed rest facilities, and micro-scale or neutral buoyancy facilities) or providing artificial gravity conditions (such as centrifuges). Data from preparatory tests, hardware and instrumentation developments, lessons learnt as well as theoretical gravity-related considerations are welcome. Included science disciplines with gravity-related topics are: − materials science − fluid mechanics − process engineering − physics − chemistry − heat and mass transfer − gravitational biology − radiation biology − exobiology and astrobiology − human physiology
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