Socio-Demographic Profiles of Naive HIV Pregnant Women and Retention to the Prevention of Mother-to-Child Transmission (PMTCT) Interventions in the East Region of Cameroon
{"title":"Socio-Demographic Profiles of Naive HIV Pregnant Women and Retention to the Prevention of Mother-to-Child Transmission (PMTCT) Interventions in the East Region of Cameroon","authors":"Ottop F. Manyi, A. Clément, M. Enow, N. Marcelin","doi":"10.4236/wja.2020.101004","DOIUrl":null,"url":null,"abstract":"Background: At enrolment into antenatal care, socio-demographic data of HIV infected pregnant women and lactating mothers are usually collected with little or no analysis done on them. This study was aimed to describe the socio-demographic profiles of naive to antiretroviral therapy (ART) HIV-infected pregnant women in the East region of Cameroon and to link this to retention in order to optimize the implementation of the prevention of mother-to-child transmission (PMTCT) interventions. Methods: A descriptive prospective study that lasted from February 2018 until February 2019 in three catchment health facilities in the East region for the recruitment and follow-up of participants who were consented HIV-infected pregnant women naive to ART. Socio-demographic, treatment compliance and adherence data were obtained by healthcare providers who were trained using a standard questionnaire that was conceived, tested and adapted for the study. Data were analyzed using Graph Prism (Graph pad 6.0, San Diego, USA). The Fisher exact and Chi-squared tests were used to establish the associations and independence between different variables at statistical significance level of p < 0.05. Results: A total of seventy (70) women were enrolled with age range varying between 15 and 40 years with a mean age of 26.5 ± 6.2 years. Loss-to-follow-up (LTFU) was observed among 17 women (24.29%). The Muslim religion, education below secondary level and the profession of housewife were significantly associated with LTFU at p = 0.01, p < 0.0001 and p = 0.0053, respectively. For participants who were retained until study endpoint, having secondary level of education or above and a profession other than housewife had a significant association (p = 0.0063), as well as being a Christian. Conclusion: Loss to follow-up in PMTCT program was associated with Muslim religion, primary level of education and the housewife occupation.","PeriodicalId":58633,"journal":{"name":"艾滋病(英文)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"艾滋病(英文)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4236/wja.2020.101004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: At enrolment into antenatal care, socio-demographic data of HIV infected pregnant women and lactating mothers are usually collected with little or no analysis done on them. This study was aimed to describe the socio-demographic profiles of naive to antiretroviral therapy (ART) HIV-infected pregnant women in the East region of Cameroon and to link this to retention in order to optimize the implementation of the prevention of mother-to-child transmission (PMTCT) interventions. Methods: A descriptive prospective study that lasted from February 2018 until February 2019 in three catchment health facilities in the East region for the recruitment and follow-up of participants who were consented HIV-infected pregnant women naive to ART. Socio-demographic, treatment compliance and adherence data were obtained by healthcare providers who were trained using a standard questionnaire that was conceived, tested and adapted for the study. Data were analyzed using Graph Prism (Graph pad 6.0, San Diego, USA). The Fisher exact and Chi-squared tests were used to establish the associations and independence between different variables at statistical significance level of p < 0.05. Results: A total of seventy (70) women were enrolled with age range varying between 15 and 40 years with a mean age of 26.5 ± 6.2 years. Loss-to-follow-up (LTFU) was observed among 17 women (24.29%). The Muslim religion, education below secondary level and the profession of housewife were significantly associated with LTFU at p = 0.01, p < 0.0001 and p = 0.0053, respectively. For participants who were retained until study endpoint, having secondary level of education or above and a profession other than housewife had a significant association (p = 0.0063), as well as being a Christian. Conclusion: Loss to follow-up in PMTCT program was associated with Muslim religion, primary level of education and the housewife occupation.
背景:在接受产前护理时,通常只收集感染艾滋病毒的孕妇和哺乳期母亲的社会人口统计数据,很少或根本没有对其进行分析。本研究旨在描述喀麦隆东部地区未接受抗逆转录病毒治疗(ART)的艾滋病毒感染孕妇的社会人口学特征,并将其与保留率联系起来,以优化预防母婴传播(PMTCT)干预措施的实施。方法:一项描述性前瞻性研究,从2018年2月持续到2019年2月,在东部地区的三个地区卫生机构进行,招募和随访同意接受抗逆转录病毒疗法的HIV感染孕妇,治疗依从性和依从性数据由接受培训的医疗保健提供者使用标准问卷获得,该问卷经过构思、测试并适用于研究。使用Graph Prism(Graph pad 6.0,San Diego,USA)分析数据。Fisher精确检验和卡方检验用于建立不同变量之间的相关性和独立性,统计学显著性水平为p<0.05。结果:共有70名女性入选,年龄范围在15至40岁之间,平均年龄为26.5±6.2岁。在17名女性(24.29%)中观察到随访失败(LTFU)。穆斯林宗教、中等以下教育和家庭主妇职业与LTFU显著相关,分别为p=0.01、p<0.0001和p=0.0053。对于保留到研究终点的参与者来说,具有中等或以上教育水平和家庭主妇以外的职业以及基督徒有显著的关联(p=0.0063)。结论:PMTCT项目随访失败与穆斯林宗教、小学教育水平和家庭主妇职业有关。