Synthesis, structure and mechanical properties of composite hydrogels for medical use

IF 0.3 Q4 CHEMISTRY, MULTIDISCIPLINARY Chemical Bulletin of Kazakh National University Pub Date : 2022-03-13 DOI:10.15328/cb1264
G. Mamytbekov, Zh.I. Beksultanov, V. Bannykh
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引用次数: 1

Abstract

The mechanism of formation of slightly crosslinked composite hydrogels based on natural agar-agar polysaccharide, synthetic polymers for medical purposes – poly-N-vinylpyrrolidone (PVP) and low-molecular plasticizers (polyethylene glycol PEG-400 and glycerin) synthesized by electron irradiation was considered from the point of view of analyzing their mechanical characteristics under various types of applied efforts. It is established that the synthesis conditions and the component composition of the initial mixture determine the formed structure of the hydrogel compositions and their mechanical properties. A new interpretation of the formation of the structure of composite hydrogels in the presence of various plasticizers is given. A detailed analysis of the deformation curves of composite hydrogels is presented taking into account the elastic-elastic, highly elastic and forced-elastic states.
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医用复合水凝胶的合成、结构和力学性能
基于天然琼脂多糖的微交联复合水凝胶的形成机制,从分析其在各种应用条件下的力学特性的角度出发,考虑了通过电子辐照合成的医用合成聚合物聚N-乙烯基吡咯烷酮(PVP)和低分子增塑剂(聚乙二醇PEG-400和甘油)。已经确定,合成条件和初始混合物的组分组成决定了水凝胶组合物的形成结构及其机械性能。对在各种增塑剂存在下复合水凝胶结构的形成给出了新的解释。详细分析了考虑弹性、高弹性和受力弹性状态的复合水凝胶的变形曲线。
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审稿时长
10 weeks
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