Effect of Uygur medicine maturants on related factors of liver energy metabolism in rats

Abstract

Objective: To investigate the effects of five Uygur medicine maturants on the related factors of liver energy metabolism in rats. Methods: After 30 days of preparation and intragastric administration, the weight changes of rats were observed. Enzyme-linked immunosorbent assay (ELISA) was used to detect Na[Formula: see text] K[Formula: see text] ATPase, Ca2[Formula: see text] Mg2[Formula: see text] ATPase and succinate dehydrogenase (SDH) activities; hepatic glycogen (HG) and muscle glycogen (MG) content, plasma triiodothyronine (T3), tetraiodothyronine (T4), and thyrotropin (TSH) content were detected. Results: The Kan (blood) quality regulator reduced the weight of rats, the Sapra regulator increased the weight of rats, the Savda maturant group, and the Balham maturant group increased the Na[Formula: see text] K[Formula: see text] ATPase, Ca2[Formula: see text] Mg2[Formula: see text] ATP, SDH activity, HG, MG, T3, T4, and TSH content of rats significantly, while the other groups had no significant effect on the energy metabolism-related factors. Conclusion: Five kinds of Uygur medicine maturants have effects on the related factors of energy metabolism in the liver of normal rats, and their elevation of serum thyroxine level is related, among which the effects of the Savda maturant group and the Balham maturant group are more significant.