Comportamiento del virus COVID-19 en una unidad de cuidados intensivos

Gilberto García-Zuluaga , David Gil-Murillo , Olga Alicia Nieto-Cárdenas
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Abstract

Introduction

The COVID-19 pandemic affected public health.

Objective

To describe the behavior of COVID-19 virus in patients with a confirmed diagnosis in the ICU of the San Juan de Dios University Hospital in Armenia between April and June 2020.

Materials and methods

Descriptive cross-sectional study. Variables are described in mean, standard deviation and confidence intervals. A comparative analysis is made by sex and outcome, analysis of variance and Chi square were performed and statistical difference was considered when the p value was less than 0.05.

Results

Sixty patients were included, 38% female and 62% male, with a significant difference by gender (p value = .003). The average age was 57 ± 1 years. Symptoms were dyspnea in 98.3%, dyspnea and cough in 38%, dyspnea and fever in 32%, and dyspnea, cough and fever in 12%. The comorbidities were arterial hypertension 33%, diabetes mellitus 21% and obesity 25%.

Dimer D (763 ng/ml), ferritin (1253 ng/ml) and LDH (426 U/l) were elevated. The oxygenation index was decreased (114 mm/Hg). Chest X-rays showed pneumonia in 78% and infiltrates in all four quadrants in 7%, and chest CT showed a ground glass image in 47% and multifocal pneumonia in 20%. The average stay in the ICU was 13.55 days, with a range between 0 and 41 days.

Conclusions

The patients presented a moderate to severe oxygenation disorder, which is why they required mechanical ventilation and prone position and 45% died.

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COVID-19病毒在重症监护病房的行为
简介新冠肺炎大流行影响了公共卫生。目的描述2020年4月至6月亚美尼亚圣胡安德迪奥斯大学医院ICU确诊患者中新冠肺炎病毒的行为。材料和方法描述性横断面研究。变量以平均值、标准差和置信区间进行描述。按性别和结果进行比较分析,当p值小于0.05时,进行方差分析和卡方分析,并考虑统计学差异。结果纳入16例患者,女性38%,男性62%,性别差异显著(p值=0.003)。平均年龄57±1岁。症状为呼吸困难98.3%,呼吸困难伴咳嗽38%,呼吸困难伴有发烧32%,呼吸困难、咳嗽伴发烧12%。合并症为动脉高压33%,糖尿病21%,肥胖25%。二聚体D(763 ng/ml)、铁蛋白(1253 ng/ml)和LDH(426 U/l)升高。氧合指数降低(114mm/Hg)。胸部X光片显示78%的患者出现肺炎,7%的患者在所有四个象限出现浸润,胸部CT显示47%的患者出现磨玻璃图像,20%的患者出现多灶性肺炎。ICU的平均住院时间为13.55天,范围在0到41天之间。结论患者表现为中度至重度氧合障碍,这就是为什么他们需要机械通气和俯卧位,45%的患者死亡。
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