Cryoformation and Properties of Dioxidine/Gelatin Systems

IF 0.7 Q4 CHEMISTRY, MULTIDISCIPLINARY Moscow University Chemistry Bulletin Pub Date : 2023-03-25 DOI:10.3103/S0027131422070124
O. I. Vernaya, A. S. Shumilkin, D. L. Karlova, A. S. Shevchenko, A. A. Makeeva, A. V. Shabatin, A. M. Semenov, T. I. Shabatina, M. Ya. Melnikov
{"title":"Cryoformation and Properties of Dioxidine/Gelatin Systems","authors":"O. I. Vernaya,&nbsp;A. S. Shumilkin,&nbsp;D. L. Karlova,&nbsp;A. S. Shevchenko,&nbsp;A. A. Makeeva,&nbsp;A. V. Shabatin,&nbsp;A. M. Semenov,&nbsp;T. I. Shabatina,&nbsp;M. Ya. Melnikov","doi":"10.3103/S0027131422070124","DOIUrl":null,"url":null,"abstract":"<p>Cryoforming of gelatin systems with the antibacterial drug dioxidine is carried out. The study considers the effect of systems’ synthesis conditions (gelatin concentration in the precursor solution) on their structural characteristics, antibacterial activity, and drug release time. The composition and structure of the dioxidine/gelatin and dioxidine/hydrolyzed collagen systems are characterized by SEM, IR, and UV spectroscopy. The disk diffusion method is used to determine the antibacterial activity of the obtained systems against <i>E. coli</i> and <i>S. aureus</i>.</p>","PeriodicalId":709,"journal":{"name":"Moscow University Chemistry Bulletin","volume":"77 1","pages":"S7 - S12"},"PeriodicalIF":0.7000,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Moscow University Chemistry Bulletin","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.3103/S0027131422070124","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Cryoforming of gelatin systems with the antibacterial drug dioxidine is carried out. The study considers the effect of systems’ synthesis conditions (gelatin concentration in the precursor solution) on their structural characteristics, antibacterial activity, and drug release time. The composition and structure of the dioxidine/gelatin and dioxidine/hydrolyzed collagen systems are characterized by SEM, IR, and UV spectroscopy. The disk diffusion method is used to determine the antibacterial activity of the obtained systems against E. coli and S. aureus.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
二氧化二胺/明胶体系的低温成型及其性能
用抗菌药物二氧化二胺进行明胶系统的低温成型。本研究考虑了体系的合成条件(前体溶液中明胶浓度)对其结构特性、抗菌活性和药物释放时间的影响。用扫描电镜、红外光谱和紫外光谱对二氧化二醇/明胶和二氧化二醇/水解胶原体系的组成和结构进行了表征。采用圆盘扩散法测定所得体系对大肠杆菌和金黄色葡萄球菌的抑菌活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Moscow University Chemistry Bulletin
Moscow University Chemistry Bulletin CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
1.30
自引率
14.30%
发文量
38
期刊介绍: Moscow University Chemistry Bulletin is a journal that publishes review articles, original research articles, and short communications on various areas of basic and applied research in chemistry, including medical chemistry and pharmacology.
期刊最新文献
Cryochemical Synthesis of Hybrid Nanoforms Based on Silver and Antibacterial Drug Dioxidine by the Low-Temperature Condensation of Vapor from the Gas Phase Interaction of Copper Clusters with Dioxidine Application of Matrix Solid-Phase Dispersion Combined with Gas Chromatography-Mass Spectrometry for the Determination of Bisphenol A in Fresh-Water Fishes Non-Destructive Analysis of Tetracycline Drugs by the Digital Colormetric Method Using a Smartphone and the Photometrix Pro® Software Indirect Determination of the Hydrogen Index of Small Volume Solutions by Digital Colorimetry
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1