Multiple intra-abdominal fungal granulomas caused by Scedosporium apiospermum effectively treated with voriconazole in a Golden Retriever

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Medical Mycology Case Reports Pub Date : 2023-09-28 DOI:10.1016/j.mmcr.2023.100611
Aritada Yoshimura , Ryuji Fukushima , Masaki Michishita , Miki Omura , Koichi Makimura , Daigo Azakami
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Abstract

Scedosporium apiospermum is a saprophytic filamentous fungus that is pathogenic to dogs. This report describes a case of S. apiospermum infection that caused multiple large peritoneal fungal granulomas in a dog with a history of jejunojejunostomy. The lesions were firmly attached to multiple organs and could not be surgically removed. In such cases, no precedent for the response to the treatment of this disease exists, and all affected dogs have died. This is the first report of an effective medical treatment for multiple intra-abdominal fungal granulomas using voriconazole.

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伏立康唑对金毛犬腹腔内由顶精子梭孢菌引起的多发真菌性肉芽肿的有效治疗
尖精子Scedosporium apispermum是一种腐生丝状真菌,对狗具有致病性。本报告描述了一例有空肠空肠造瘘史的狗的精子细胞感染,导致多个腹膜大真菌肉芽肿。病变牢固地附着在多个器官上,无法通过手术切除。在这种情况下,对这种疾病的治疗没有反应的先例,所有受影响的狗都已经死亡。这是首次报道使用伏立康唑治疗多发性腹腔内真菌性肉芽肿的有效药物治疗方法。
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来源期刊
Medical Mycology Case Reports
Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
4.00
自引率
0.00%
发文量
48
审稿时长
47 days
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