Systemic fungal infections: A pharmacist/researcher perspective

IF 5.7 2区 生物学 Q1 MYCOLOGY Fungal Biology Reviews Pub Date : 2023-01-01 DOI:10.1016/j.fbr.2022.11.001
Abbygail C. Spencer , Katelyn R. Brubaker , Sylvie Garneau-Tsodikova
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系统性真菌感染:药剂师/研究人员的观点
系统性真菌感染的患病率正在上升,特别是在免疫功能低下的患者和术后患者中。系统性真菌感染的增加导致抗真菌药物的使用增加,这反过来又导致耐药率上升,正如2019年疾病控制和预防中心《抗菌素耐药性威胁报告》中增加的真菌病原体数量所示。不幸的是,很少有新的抗真菌药物进入市场来对抗这些不断增加的耐药性。在这篇综述中,我们介绍了抗真菌药物的现状,并探讨了正在开发和潜在上市的药物。我们还讨论了经验性和靶向性抗真菌治疗的适应症,以及将抗真菌药物作为抗菌药物管理计划的一部分的必要性,这些计划主要关注抗菌药物。
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来源期刊
CiteScore
10.60
自引率
0.00%
发文量
36
期刊介绍: Fungal Biology Reviews is an international reviews journal, owned by the British Mycological Society. Its objective is to provide a forum for high quality review articles within fungal biology. It covers all fields of fungal biology, whether fundamental or applied, including fungal diversity, ecology, evolution, physiology and ecophysiology, biochemistry, genetics and molecular biology, cell biology, interactions (symbiosis, pathogenesis etc), environmental aspects, biotechnology and taxonomy. It considers aspects of all organisms historically or recently recognized as fungi, including lichen-fungi, microsporidia, oomycetes, slime moulds, stramenopiles, and yeasts.
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