Clinical analysis of the efficacy of thalidomide combined with finger pointing in the treatment of ankylosing spondylitis

Journal of Holistic Integrative Pharmacy Pub Date : 2023-03-01 DOI:10.1016/S2707-3688(23)00095-X

Liangyi QIN , Jing LAI

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Abstract

Objective

This study aims to investigate the different treatment protocols for ankylosing spondylitis (AS) in the clinic. In this paper, finger point therapy and thalidomide were proposed to be used in the treatment of the disease, and the effects were evaluated.

Methods

Sixty-eight patients with AS were randomly divided into two groups: the control group and the treatment group, with 34 cases in each group. The two groups were given different medication regimens to compare the differences in symptoms and signs and efficacy after different regimens were implemented.

Results

After treatment, the experimental outcomes of the Schober test, occipital wall distance, finger-ground test, blood sedimentation, C-reactive protein, IL-6, TNF-α, and ASDAS index level in the treatment group were significantly different from those in the control group (P<0.05), and the treatment group's overall effective rate was 100% significantly higher than that of the control group (χ²=7.988, P< 0.05).

Conclusion

The symptoms and signs of patients with AS could be significantly improved by thalidomide with finger point therapy.

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沙利度胺联合指法治疗强直性脊柱炎的临床疗效分析

目的探讨强直性脊柱炎（AS）的不同治疗方案。本文建议将指点疗法和沙利度胺用于该病的治疗，并对其效果进行评价。方法将68例AS患者随机分为对照组和治疗组，每组34例。两组给予不同的用药方案，比较不同方案实施后症状体征和疗效的差异。结果治疗后，治疗组的Schober试验、枕壁距离、指地试验、血沉、C反应蛋白、IL-6、TNF-α和ASDAS指数水平的实验结果与对照组有显著性差异（P<；0.05），治疗组总有效率明显高于对照组100%（χ2=7.988，P<；0.05）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Holistic Integrative Pharmacy

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