{"title":"Resultados maternos y fetales en pacientes con preeclampsia severa e hipotiroidismo primario. Estudio de casos y controles","authors":"J.G. Vázquez Rodríguez , C.E. Penagos Chanona , J.G. Vázquez Arredondo","doi":"10.1016/j.gine.2023.100846","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Primary hypothyroidism has adverse effects on maternal and fetal outcomes. In the scenario of severe preeclampsia (SP), the impact on the binomial may be greater.</p></div><div><h3>Objective</h3><p>To compare maternal and fetal outcomes in patients with SP and primary hypothyroidism.</p></div><div><h3>Material and methods</h3><p>This was a case-control study in 58 pregnant patients with SP admitted to the Intensive Care Unit of a High Specialty Unit in Mexico City attended from January 2018 to December 2021. The case group was formed with 29 patients with pre-pregnancy primary hypothyroidism and the control group with 29 age-matched patients with normal pre-pregnancy thyroid function. Their overall data and maternal and fetal outcomes were compared. Descriptive statistics, chi-square test, and Student's t-test with the SPSS version 20 programme were used. A p-value<<!--> <!-->0.05 was significant.</p></div><div><h3>Results</h3><p>No differences were found in age (p<!--> <!-->=<!--> <!-->.8292), parity (p<!--> <!-->=<!--> <!-->1), systolic (p<!--> <!-->=<!--> <!-->.7229) and diastolic (p<!--> <!-->=<!--> <!-->.5498) blood pressure, caesarean section (p<!--> <!-->=<!--> <!-->.812), intrapartum haemorrhage (p<!--> <!-->=<!--> <!-->.812), p<!--> <!-->=<!--> <!-->.3558), anaesthetic technique (p<!--> <!-->=<!--> <!-->.5786), obstetric complications, Intensive Care Unit stay (p<!--> <!-->=<!--> <!-->.6181), and mortality. There were no differences in the products: singleton pregnancy (p<!--> <!-->=<!--> <!-->.912), gestational age (p<!--> <!-->=<!--> <!-->.8901), weight (p<!--> <!-->=<!--> <!-->.3338), Apgar score minute one and five, prematurity (p<!--> <!-->=<!--> <!-->.8701), intensive care (p<!--> <!-->=<!--> <!-->.0623), in utero mortality (n<!--> <!-->=<!--> <!-->4 vs n<!--> <!-->=<!--> <!-->4), and mortality at birth (n<!--> <!-->=<!--> <!-->2 vs n<!--> <!-->=<!--> <!-->0).</p></div><div><h3>Conclusions</h3><p>Maternal and fetal outcomes were similar. The cases with uncontrolled thyroid did not show adverse clinical effects.</p></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":null,"pages":null},"PeriodicalIF":0.1000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinica e Investigacion en Ginecologia y Obstetricia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0210573X23000163","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Primary hypothyroidism has adverse effects on maternal and fetal outcomes. In the scenario of severe preeclampsia (SP), the impact on the binomial may be greater.
Objective
To compare maternal and fetal outcomes in patients with SP and primary hypothyroidism.
Material and methods
This was a case-control study in 58 pregnant patients with SP admitted to the Intensive Care Unit of a High Specialty Unit in Mexico City attended from January 2018 to December 2021. The case group was formed with 29 patients with pre-pregnancy primary hypothyroidism and the control group with 29 age-matched patients with normal pre-pregnancy thyroid function. Their overall data and maternal and fetal outcomes were compared. Descriptive statistics, chi-square test, and Student's t-test with the SPSS version 20 programme were used. A p-value< 0.05 was significant.
Results
No differences were found in age (p = .8292), parity (p = 1), systolic (p = .7229) and diastolic (p = .5498) blood pressure, caesarean section (p = .812), intrapartum haemorrhage (p = .812), p = .3558), anaesthetic technique (p = .5786), obstetric complications, Intensive Care Unit stay (p = .6181), and mortality. There were no differences in the products: singleton pregnancy (p = .912), gestational age (p = .8901), weight (p = .3338), Apgar score minute one and five, prematurity (p = .8701), intensive care (p = .0623), in utero mortality (n = 4 vs n = 4), and mortality at birth (n = 2 vs n = 0).
Conclusions
Maternal and fetal outcomes were similar. The cases with uncontrolled thyroid did not show adverse clinical effects.
期刊介绍:
Una excelente publicación para mantenerse al día en los temas de máximo interés de la ginecología de vanguardia. Resulta idónea tanto para el especialista en ginecología, como en obstetricia o en pediatría, y está presente en los más prestigiosos índices de referencia en medicina.