Maternal prepregnancy body mass index, gestational weight gain, and allergic diseases in children: A systematic review and meta-analysis

IF 8 2区医学 Q1 ENDOCRINOLOGY & METABOLISM Obesity Reviews Pub Date : 2023-10-25 DOI:10.1111/obr.13653

Hongbiao Yu, Ling Chen, Yulin Zhang

{"title":"Maternal prepregnancy body mass index, gestational weight gain, and allergic diseases in children: A systematic review and meta-analysis","authors":"Hongbiao Yu, Ling Chen, Yulin Zhang","doi":"10.1111/obr.13653","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Several studies have investigated a link between maternal preconception body mass index, gestational weight gain (GWG), and the risk of childhood allergic diseases, but the conclusions of these studies were inconsistent. This review aimed to evaluate the relationship based on existing studies. We eventually included 18 cohort studies. The findings indicated that both maternal preconception overweight or obesity increased the risk of childhood wheezing (overweight: risk ratio (RR) 1.09, 95% confidence interval (CI) 1.04–1.15; obesity: RR 1.24, 95% CI 1.12–1.38) and asthma (overweight: RR 1.18, 95% CI 1.05–1.32; obesity: RR 1.34, 95% CI 1.13–1.58), and the risk of childhood wheezing increased with continuous prepregnancy BMI changes (per 5 kg/m<sup>2</sup> increase) (RR 1.10, 95% CI 1.05–1.15). Preconception underweight may elevate the risk of childhood eczema ever (RR 1.05, 95% CI 1.02–1.09) and current eczema (RR 1.20, 95% CI 1.05–1.37), and preconception overweight may reduce the risk of childhood eczema ever (RR 0.98, 95% CI 0.96–0.99). No statistically significant association between GWG and the risk of allergic diseases in children was found. Preconception weight management is encouraged for the prevention of allergic diseases in children.</p>\n </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"25 2","pages":""},"PeriodicalIF":8.0000,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obesity Reviews","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/obr.13653","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Several studies have investigated a link between maternal preconception body mass index, gestational weight gain (GWG), and the risk of childhood allergic diseases, but the conclusions of these studies were inconsistent. This review aimed to evaluate the relationship based on existing studies. We eventually included 18 cohort studies. The findings indicated that both maternal preconception overweight or obesity increased the risk of childhood wheezing (overweight: risk ratio (RR) 1.09, 95% confidence interval (CI) 1.04–1.15; obesity: RR 1.24, 95% CI 1.12–1.38) and asthma (overweight: RR 1.18, 95% CI 1.05–1.32; obesity: RR 1.34, 95% CI 1.13–1.58), and the risk of childhood wheezing increased with continuous prepregnancy BMI changes (per 5 kg/m² increase) (RR 1.10, 95% CI 1.05–1.15). Preconception underweight may elevate the risk of childhood eczema ever (RR 1.05, 95% CI 1.02–1.09) and current eczema (RR 1.20, 95% CI 1.05–1.37), and preconception overweight may reduce the risk of childhood eczema ever (RR 0.98, 95% CI 0.96–0.99). No statistically significant association between GWG and the risk of allergic diseases in children was found. Preconception weight management is encouraged for the prevention of allergic diseases in children.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

母亲孕前体重指数、妊娠期体重增加和儿童过敏性疾病：一项系统综述和荟萃分析。

几项研究调查了母亲孕前体重指数、妊娠期体重增加（GWG）和儿童过敏性疾病风险之间的联系，但这些研究的结论并不一致。本综述旨在根据现有研究评估这种关系。我们最终纳入了18项队列研究。研究结果表明，母亲先入为主的超重或肥胖都会增加儿童喘息的风险（超重：风险比（RR）1.09，95%置信区间（CI）1.04-1.15；肥胖：RR 1.24，95%CI 1.12-1.38）和哮喘（超重：RR 1.18，95%CI 1.05-1.32；肥胖：RR 1.34，95%CI1.13-1.58），并且儿童喘息的风险随着孕前BMI的持续变化而增加（每增加5 kg/m2）（RR 1.10，95%CI 1.05-1.15）。孕前体重不足可能会增加儿童湿疹（RR 1.05，95%CI 1.02-1.09）和当前湿疹（RR 1.20，95%CI1.05-1.37）的风险，超重可降低儿童患湿疹的风险（RR 0.98，95%CI 0.96-0.99）。鼓励进行孕前体重管理，以预防儿童过敏性疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Obesity Reviews 医学-内分泌学与代谢

CiteScore

19.30

自引率

1.10%

发文量

130

审稿时长

1 months

期刊介绍： Obesity Reviews is a monthly journal publishing reviews on all disciplines related to obesity and its comorbidities. This includes basic and behavioral sciences, clinical treatment and outcomes, epidemiology, prevention and public health. The journal should, therefore, appeal to all professionals with an interest in obesity and its comorbidities. Review types may include systematic narrative reviews, quantitative meta-analyses and narrative reviews but all must offer new insights, critical or novel perspectives that will enhance the state of knowledge in the field. The editorial policy is to publish high quality peer-reviewed manuscripts that provide needed new insight into all aspects of obesity and its related comorbidities while minimizing the period between submission and publication.