Rethinking about acupuncture intervention opportunity based on dynamic perspective of inflammatory response.

Dong Lin, Meng Gong, Shi-Yi Qi, Si-Jia Zhang, Ying Huang, Zhi-Ting Wu
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Abstract

Acupuncture and moxibustion therapies are widely used in the field of anti-inflammation, but the dynamic characteristics of inflammatory response with time in the modern biological mechanism research has been ignored to some extent. Therefore, the body surface intervention system represented by acupuncture-moxibustion urgently needs to rebuild the research perspective oriented to the complex immune regulation model, and then to explore the opportunity of acupuncture-moxibustion anti-inflammatory intervention according to the dynamic change process of inflammatory response. Through comparative analysis on the ancient and modern acupuncture-moxibustion immune regulation, and starting from the construction of clinical body surface intervention system, we propose that grasping the appropriate "intervention opportunity" is an important entry point that cannot be ignored to effectively "pry" inflammatory response.

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基于炎症反应动力学视角对针灸干预时机的再思考。
针灸疗法在抗炎领域有着广泛的应用,但在现代生物学机制研究中,炎症反应随时间的动态特征在一定程度上被忽视了。因此,以针灸为代表的体表干预系统迫切需要重建面向复杂免疫调节模型的研究视角,进而根据炎症反应的动态变化过程,探索针灸抗炎干预的时机。通过对古代和现代针灸免疫调节的比较分析,并从临床体表干预体系的构建入手,提出把握适当的“干预时机”是有效“撬动”炎症反应不可忽视的重要切入点。
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