A Radiohistographic Analysis of Growth Factor-Mediated Sinus Augmentation in Atrophic Maxillae: A 30-Month Follow-up Study.

Pamidimarri Sai Divya Gayatri, Amanna Baron Tarun Kumar, Rucha Shah, Triveni Mavinakote Gowda, Vempati Satya Krishna
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Abstract

A total of 20 atrophic maxillary sinuses were augmented with recombinant human platelet-derived growth factor BB (rhPDGF-BB), alloplast, and bovine xenograft using a direct approach. CBCT imaging was performed at baseline, immediately postoperatively, and at 6 and 30 months postoperatively. A histologic evaluation revealed the bone bridging and bone regenerative efficacy of the graft material. Radiographic evaluation determined the ridge height (H) and volume of the graft (V) to be as 3.02 ± 1.35 mm at baseline (H0), 15.18 ± 2.52 mm (H1) and 1,106.10 ± 398.84 mm3 (V1) immediately postoperatively, 14.79 ± 2.30 mm (H2) and 1,086.95 ± 396.86 mm3 (V2) at 6 months, and 1,058 ± 391.83 mm3 (V3) at 30 months, with a significant gain in the residual ridge height at 6 months and no significant loss or gain in sinus volume postoperatively.

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生长因子介导的萎缩性上颌窦扩张的放射组学分析:一项30个月的随访研究。
用重组人血小板衍生生长因子BB(rhPDGF-BB)、同种异体移植物和牛异种移植物直接扩增总共20个萎缩的上颌窦。在基线、术后立即以及术后6个月和30个月进行CBCT成像。组织学评估显示了移植物材料的骨桥接和骨再生功效。射线评估确定移植物的脊高(H)和体积(V)在基线时为3.02±1.35 mm(H0),术后立即为15.18±2.52 mm(H1)和1106.10±398.84 mm3(V1),6个月时为14.79±2.30 mm(H2)和1086.95±396.86 mm3(V2),30个月时分别为1058±391.83 mm3(V3),6个月时残余嵴高度显著增加,术后窦体积无显著损失或增加。
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