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Vertical Guided Bone Regeneration: Leukocyte and PRF Bone-Block vs A Mixture of Autogenous Bone with DBBM. A Split-Mouth Randomized Controlled Trial with Follow-up Up to 1 Year After Implant Loading.
Pub Date : 2025-02-13 DOI: 10.11607/prd.7338
Rutger A L Dhondt, Marc Quirynen, Simone Cortellini, Pierre Lahoud, Andy Temmerman

Background: Oral implants require adequate bone support, which is often facilitated by bone augmentation when bone volume is insufficient. Autogenous bone (AB) has been considered the 'gold standard' for such procedures due to its osteogenic properties, but it necessitates a second surgical site, which increases patient morbidity. Trial Design and Methods: This study was a randomized, double-blind, split-mouth clinical trial comparing L PRF (leukocyte-platelet rich fibrin) bone-block grafts against a composite graft mixture of 50% AB with 50% deproteinized bovine bone mineral (DBBM) for vertical guided bone regeneration (GBR). The trial included 6 patients needing bilateral vertical GBR before implant placement. A dense polytetrafluoroethylene (d-PTFE) membrane was used for both test and control sites. The primary outcome measure was vertical bone height (VBH) gain, assessed via cone beam computed tomography (CBCT) at 9 and 25 months post-operation.

Results: There was no significant difference in VBH gain between the test and control sites at any time points, with a mean VBH gain at implant placement of 4.6 ± 3.0 mm for test sites and 5.2 ± 2.7 mm for control sites. At 1 year after loading of the implants the VBH gain was 3.0 ± 2.8 mm for test sites and 3.8 ± 2.6 mm for control sites (P value 0.96). Complications were minimal and included one implant loss due to infection in a test site.

Conclusions: The L-PRF bone block could be a viable alternative to the composite graft, potentially reducing the need for harvesting bone from a second surgical site. Future studies with larger sample sizes are needed to confirm these findings and to explore the biological benefits of integrating the L-PRF bone-block into bone graft materials for oral implantology.

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引用次数: 0
Subperiosteal Tissue Tacking as a Novel Approach to Recreate the Lost Hard and Soft Tissue Framework: Case Series and Illustrated Clinical Considerations.
Pub Date : 2025-02-13 DOI: 10.11607/prd.7382
Alexander DeGreef, Ivaylo Pashov, Ventseslav Stankov, Antonia Nikolova, Stavros Pelekanos, Leonardo Mancini, Eric Van Dooren, Andy Temmerman, Ana Castro

As stability is a key determinant of successful regeneration, this paper introduces tack engagement as a novel alternative to conventional suturing techniques, aimed at improving the positioning and fixation of autogenous tissue grafts. Rigid tack engagement, a widely utilized technique in guided bone regeneration (GBR) protocols for securing membranes, offers a stable and time-efficient solution that mitigates the risks of early graft displacement resulting from suturing or delayed volume changes due to physiological healing processes or unintentional patient oral habits. Subperiosteal tissue tacking represents a promising alternative technique for managing small to moderate tissue defects, mitigating various biological and practical obstacles. Within the limitations of this current report, tacks provide a variety of practical benefits for tissue fixation, rendering them particularly useful in staged implant placement procedures. Further research is necessary to comprehensively assess the benefits and potential constraints of this innovative approach.

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引用次数: 0
The Slice Harvesting Technique for Tuberosity Soft Tissue Grafts: A Case Report.
Pub Date : 2025-02-13 DOI: 10.11607/prd.7465
Vincent Ronco

Constant efforts are made to trigger simpler, faster and less invasive surgical approaches to harvest autologous connective tissue grafts. While the palate is considered as a gold standard, its association with complications and patient discomfort have led clinicians to explore alternative sites like the tuberosity. However, current tuberosity harvesting techniques face several limitations. Through a multiple recessions clinical case intended as a proof of concept, this article describes a novel harvesting technique based on a gingivectomy that triggers the tuberosity tangentially. Clinical, aesthetic, and patient outcomes were monitored at 7 days, 14 days, 1 month, and 3 years at the grafted site as well as at the tuberosity. Multiple harvestings were conducted at the tuberosities offering connective tissue grafts suitable for micrografting. Harvested tuberosities healed completely without complication, and the patient reported no discomfort. At the grafted site, both aesthetic and functional results were maintained for up to 3 years. The Slice Harvesting Technique offers a promising alternative for tuberosity tissue harvesting, with critical advantages including high indication rate, simplicity, speed, safety, and the ability to provide user-friendly connective tissue grafts. Besides, the technique could also appear sustainable and favor the regrow of tuber for multiple rounds of harvesting.

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引用次数: 0
Relationship Between Sagittal Root Position and Alveolar Wall Thickness of Maxillary Teeth in the Esthetic Area for Immediate Implant Treatment Planning in a Peruvian Population. 在秘鲁人群中,即刻种植治疗计划的美容区上颌齿矢状根位置和牙槽壁厚度之间的关系。
Pub Date : 2025-01-24 DOI: 10.11607/prd.6854
Daniel Alonso Kim Espinoza-Espinoza, Nelly María García-Madueño, Julissa Amparo Dulanto-Vargas, Fiorella Estefanie Lamas-Castillo, Kilder Maynor Carranza-Samanez, Christian Alexander Loo

The purpose of this retrospective study was to assess facial and palatal alveolar wall thickness (AWT) in relation to sagittal root position (SRP) of maxillary anterior teeth using CBCT. A total of 102 CBCT images (60 women, 42 men) of maxillary anterior teeth were reviewed. SRP was classified according to Kan's classification, and AWT was evaluated at coronal (4 mm from the CEJ), mid-root, and apical (2 mm from the apex) levels of the facial and palatal aspects. Sex, age, and tooth type were analyzed as secondary variables. The SRP distribution was 76.6% class I, 11.3% class II, 0.8% class III, and 11.3% class IV. AWT, from thickest to thinnest, was found in palatal apical, then mid-root, then coronal levels, followed by facial coronal, then mid-root, then apical levels. AWT was thickest in SRP class II, followed by classes I and III, and least thick in class IV at all measured areas (P < .05). A significantly higher AWT was associated with class I in central incisors, class II in canine teeth and in men, and class IV in central incisors and canines.

目的:应用锥形束计算机断层扫描技术(CBCT)评价面腭牙槽壁厚度(AWT)与上颌前牙矢状根位置(SRP)的关系。SRP根据Kan分类法进行分类,AWT在面部和腭部的冠状面(距离牙骨质层交界处4 mm)、中根和根尖(距离根尖2 mm)水平进行评估。分析了性别、年龄和牙齿类型的次要变量。结果:SRPⅠ类分布占76.6%,Ⅱ类分布占11.3%,Ⅲ类分布占0.8%,Ⅳ类分布占113%
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引用次数: 0
A Novel 3D Tunneling (3DT) Surgical Technique for the Treatment of Gingival Recessions with Reconstruction of the Deficient Interdental Papilla and Interproximal Attachment Regeneration: A Case Series. 新型三维隧道手术技术(3DT)治疗牙龈萎缩,重建缺损的牙间乳头和近端附着体再生:病例系列。
Pub Date : 2025-01-24 DOI: 10.11607/prd.6960
Emilia Kazarian, Kristina Inozemtseva, Evgenia Lebedeva

Current concepts in periodontology emphasize the interproximal attachment as an important distinguishing aspect with significant influence, making it a key diagnostic and prognostic factor. Complete regeneration of the interproximal clinical attachment has become a primary determinant of periodontal success. Since the mid-20th century, numerous articles have been published on root coverage procedures, mostly for nonproximal gingival recessions. When it comes to the interdental area, the literature does not inspire the same level of confidence. This case series introduces an innovative 3D tunneling surgical technique for gingival papilla reconstruction and supra-alveolar interproximal attachment regeneration. The technique is described step by step and shown with three selected clinical cases of multiple bilateral adjacent gingival recessions (types 2 and 3) in the anterior mandible with 6.5 years of follow-up. A total of 18 proximal, midbuccal, and midlingual recessions were treated simultaneously. Up to 88.9% of mean root coverage was achieved in the proximal area. Within its limits, this case series demonstrates the possibility of treating gingival recessions with deficient papillae in the anterior mandible, achieving a significant clinical improvement with long-term stability.

背景:当前的牙周病学概念强调近端间附着物的重要区别,认为其作为关键诊断和预后因素具有重要的影响意义。近端间临床附着的完全再生已成为牙周成功的主要决定因素。自 20 世纪中叶以来,发表了大量关于牙根覆盖程序的文章,但大多针对非近端牙龈凹陷。而对于牙间区域,文献并没有给予同样的信心:本研究旨在介绍一种创新的三维隧道手术技术,用于龈乳头重建和牙槽上近端附着体再生:对该技术进行了逐步描述,并在三个选定的临床病例中进行了展示,这三个病例均为下前牙区双侧多发邻面2型和3型牙龈退缩,随访结果长达6.5年:结果:共同时治疗了18个近端、颊中和舌中凹陷。近端区域的平均牙根覆盖率高达 88.9%:本研究在一定范围内证明了治疗下颌前牙区乳头缺损的牙龈凹陷的可能性,并取得了显著的临床改善和长期稳定性。
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引用次数: 0
Clinical Implications of Buccinator Fiber Attachment on Interventions to Enhance Peri-implant Keratinized Mucosa: An Ex Vivo Study. Buccinator纤维附着对旨在增强种植体周围角化粘膜的干预措施的临床意义:一项体外研究。
Pub Date : 2025-01-24 DOI: 10.11607/prd.6955
Ángel Insua, Yolanda Macias, Yolanda Gañan, Luis Ortiz-González, Gerardo Ruales-Suárez, Alberto Monje

A clinical observation usually encountered after vestibuloplasty, or after interventions aiming to deepen the vestibule with or without simultaneous free epithelialized grafts in the posterior ridges, is that the vestibule can be subjected to major dimensional changes attributed to the buccinator fiber attachment. Therefore, this study aimed to assess the attachment of the buccinator muscles in relation to other anatomical landmarks. An ex vivo study was performed in cadaver heads to explore the association of fiber attachment in relation to the distance from the crestal aspect of the edentulous alveolar process (CAP) and the vestibular depth (VD), crestal band of keratinized mucosa (KM), and ridge height (RH). Interestingly, VD and KM were found to be strongly correlated. Likewise, VD/ KM and CAP-BUC (CAP to the most coronal insertion of the buccinator muscle) were also correlated. CAP-BUC was negatively correlated with RH. Accordingly, the more atrophic the alveolar ridge (ie, more noticeable in the mandible), the shallower the vestibule, the smaller the crestal band of KM, and the greater crestal attachment of the buccinator muscular fibers. This may be the reason why the graft is subjected to major dimensional changes whenever a free epithelialized graft is performed in the posterior ridges to enhance the peri-implant soft tissue phenotype and deepen the vestibule.

在前庭成形术或旨在加深前庭的干预措施后,无论是否在后嵴同时进行游离上皮化移植物,通常会遇到一个临床观察结果,即它们会因颊纤维附着而发生重大的尺寸变化。因此,本研究旨在评估颊肌与其他解剖标志的附着关系。在尸体头部进行了一项离体研究,以探索纤维附着与无牙牙槽突(CAP)冠面距离、前庭深度(VD)、角化粘膜冠带(KM)和嵴高度(RH)的关系。有趣的是,VD和KM被发现是强相关的。同样,VD/KM和CAP-BUC也存在相关性。CAP-BUC与RH呈负相关。因此,牙槽嵴越萎缩(在下颌骨中更明显),前庭越浅,KM的嵴带越小,颊肌纤维的嵴附着越多。这可能是为什么每当在后嵴进行游离上皮化移植物以增强种植体周围软组织表型并加深前庭时,移植物都会发生重大的尺寸变化的原因。
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引用次数: 0
Impact of Calcium Hydroxide, Sodium Ascorbate, and Sodium Thiosulfate on the Bond Strength of Composite Restorations to Bleached Dentin. 氢氧化钙、抗坏血酸钠和硫代硫酸钠对漂白牙本质复合修复体粘接强度的影响
Pub Date : 2025-01-24 DOI: 10.11607/prd.6987
Maíra Prado, Juliana das Neves Marques Machado, Maria Eduarda Perez Cruz Santos, Marina Carvalho Prado, Carolina Oliveira de Lima, Silvia Renata Marski, Heloísa Carla Dell Santo Gusman, Renata Antoun Simão

This study evaluated the impact of using calcium hydroxide or antioxidant agents on the bond strength of adhesive restorations to bleached dentin. A total of 40 teeth were prepared and allocated into eight groups, first divided according to the surface treatment after bleaching (no treatment or application of calcium hydroxide, 10% sodium ascorbate, or 5% sodium thiosulfate for 10 minutes) and then according to the time of final restoration after treatment (immediate or after 7 days). Sodium perborate with 20% hydrogen peroxide was applied for 3 weeks using a developed artificial pulp chamber, with peroxide replacements provided every week. Composite resin restoration was performed, followed by a microtensile test. Then, specimens were analyzed using a stereomicroscope and scanning electron microscopy (SEM). Data were submitted to Kruskal-Wallis and Dunn tests (P < .05). The bond strength of nonbleached teeth was similar to the groups restored after 7 days of bleaching (P < .05). The lowest bond strength values were seen in groups restored immediately after bleaching (P < .05). In all groups, there was a considerable predominance of adhesive fractures. Delaying the final restoration of teeth submitted to nonvital bleaching by 7 days increased the bond strength. The immediate restoration of bleached teeth after using 10% sodium ascorbate or 5% sodium thiosulfate for 10 minutes showed unsatisfactory results. Irrespective of the dentin protocol applied before adhesion, bond strength values will be satisfactory when delaying the final restoration and unsatisfactory when immediately performing the final restoration. Therefore, after nonvital tooth bleaching, clinicians should always delay the final restoration for a minimum period of 7 days.

本研究评估了使用氢氧化钙或抗氧化剂对漂白牙本质粘接修复体粘接强度的影响。研究人员制备了 40 颗牙齿,并根据漂白后的表面处理(是否使用氢氧化钙、10% 抗坏血酸钠和 5%硫代硫酸钠 10 分钟)和最终修复时间(即刻或 7 天后)将其分为 8 组。使用已开发的人工牙髓室对 20%过氧化氢的过硼酸钠进行为期 3 周的应用,每周更换一次。进行复合树脂修复并进行微拉伸测试。然后,使用体视显微镜和扫描电镜对试样进行分析。数据经 Kruskal-Wallis 和 Dunn 检验(p
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引用次数: 0
Managing Patient Treatment Through Deming's PDCA Cycle: A Standardized Approach in Phases That Adds Value to Dental Care.
Pub Date : 2025-01-24 DOI: 10.11607/prd.6918
Andrea Faggian, Diego Capri, Stefano Gracis
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引用次数: 0
Evidence-Based Treatment of Peri-implantitis?
Pub Date : 2025-01-24 DOI: 10.11607/prd.2025.1.e
Mario Roccuzzo
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引用次数: 0
A Volume-Stable Collagen Matrix (VCMX) to Treat Single Gingival Recessions Associated with Partially Restored Noncarious Cervical Lesions: A Case Series. 一种新的体积稳定的胶原基质(VCMX)治疗与部分修复的非龋性宫颈病变相关的单牙龈退缩:一系列病例。
Pub Date : 2025-01-24 DOI: 10.11607/prd.6924
Manuela Maria Viana Miguel, Ingrid Fernandes Mathias-Santamaria, Marina Strelow Kopereck, Thiago Marchi Martins, Marcelo Pereira Nunes, Mauro Pedrine Santamaria

Collagen matrices have been developed as possible connective tissue graft substitutes to overcome patient discomfort, undesired palatal healing, and the limited amount of donor tissue. The aim of this case series is to assess a coronally advanced flap (CAF) with a volume-stable collagen matrix (VCMX) to treat single gingival recessions (GRs) associated with partially restored noncarious cervical lesions (NCCLs). Twelve patients diagnosed with single GRs (type 1; RT1) + NCCL (B+) were included in this study and received a restorative approach (partial composite resin with an apical margin 1 mm beyond the estimated cementoenamel junction [CEJ]) and a surgical approach (CAF+VCMX). Clinical and patient-centered assessments were recorded from 10 patients at baseline and 6 months postoperatively. Significant recession reduction (2.1 mm), clinical attachment level gain (1.34 mm), and combined defect coverage (51.67%) were observed at 6 months. The estimated root coverage was 69.48%, obtained using the estimated CEJ. No difference in keratinized tissue width was observed over time. A 0.42-mm gain in gingival thickness was observed after 6 months (P = .002) as well as an improvement in patient satisfaction due to better esthetics (P < .001). Within the present study's limitations, CAF+VCMX provided a significant improvement in treating single GRs combined with a partially restored NCCL (B+).

胶原基质已被开发为可能的结缔组织移植物替代品,以克服患者的不适、不希望的腭部愈合和有限的供体组织。本病例系列的目的是评估一种具有新型体积稳定胶原基质(VCMX)的冠状动脉晚期皮瓣(CAF),以治疗与部分修复的非龋性宫颈病变(NCCL)相关的单牙龈退缩(GR)。本研究纳入了12名被诊断为单一GR RT1+NCCL(B+)的患者,他们接受了一种修复性部分树脂复合材料和一种手术方法CAF+VCMX。在基线和术后6个月记录10名患者的临床和以患者为中心的评估。在6个月时观察到显著的衰退减少(RecRed:2.1mm)、临床附着水平增加(CAL:1.34mm)和51.67%的联合缺陷覆盖率(CDC)。使用估计的CEJ获得的估计根覆盖率(RC)为69.48%。随着时间的推移,没有观察到角化组织宽度(KTW)的差异。6个月后,观察到牙龈厚度(GT)增加了0.42 mm(p=0.002),并且由于更好的美学效果,患者满意度有所提高(p
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引用次数: 0
期刊
The International journal of periodontics & restorative dentistry
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