{"title":"Design of a high-sensitivity polymer double-slot waveguide sensor for point-of-care biomedical applications","authors":"S. Prasanna Kumaar, A. Sivasubramanian","doi":"10.1016/j.sintl.2023.100255","DOIUrl":null,"url":null,"abstract":"<div><p>Silicon photonics is a rapidly developing field that offers cost-effective biosensors with improved sensitivity and the potential for interconnecting with other electronic devices for instant disease diagnosis. The Mach Zehnder interferometer architecture (MZI) is a key technology for biosensors, as it detects changes in refractive index (RI) caused by the presence of biomolecules. In this study, a silicon-polymer double-slot waveguide-based MZI was designed, with a small mode area and a large evanescent field to enhance light-analyte interaction. The waveguide was optimized by converting a normal slot waveguide into a double-slot waveguide with varying slot widths. In transmission spectrum, the wavelength shift was measured for both normal and disease samples. Additionally, the loss at a specific wavelength was analyzed to understand the impact of the biomolecule on the sensor performance. The results show that this sensor has a high sensitivity of 2.39 X10^5 nm/RIU, making it a promising candidate for biosensing applications.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100255"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sensors International","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666351123000293","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Silicon photonics is a rapidly developing field that offers cost-effective biosensors with improved sensitivity and the potential for interconnecting with other electronic devices for instant disease diagnosis. The Mach Zehnder interferometer architecture (MZI) is a key technology for biosensors, as it detects changes in refractive index (RI) caused by the presence of biomolecules. In this study, a silicon-polymer double-slot waveguide-based MZI was designed, with a small mode area and a large evanescent field to enhance light-analyte interaction. The waveguide was optimized by converting a normal slot waveguide into a double-slot waveguide with varying slot widths. In transmission spectrum, the wavelength shift was measured for both normal and disease samples. Additionally, the loss at a specific wavelength was analyzed to understand the impact of the biomolecule on the sensor performance. The results show that this sensor has a high sensitivity of 2.39 X10^5 nm/RIU, making it a promising candidate for biosensing applications.