Review on the recent development on ionic liquid promoted domino reactions in synthesis of eco-compatible and complex molecules

Sethuraman Indumathi, Imran Khan
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Abstract

Ionic liquid (IL) catalysed organic syntheses have emerged as a great approach to improve synthetic productivity. Particularly IL catalyzed domino reactions enable the synthesis of organic compounds with high regio/stereoselectivity from simple starting materials. Being the designer solvents, IL promoted domino reactions lead to the eco-friendly green synthetic steps with high-percentage yield. In this review, we have summarized the IL catalyzed one pot tandem reactions for the synthesis of highly functionalized organic molecules. The reaction mechanisms, regioselectivity, and stereoselectivity of the reactions are described in detail. This review has been summarized to extend the synthetic applications of IL catalyzed domino reactions in future.

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离子液体促进多米诺反应合成生态相容性复杂分子的研究进展
离子液体(IL)催化的有机合成已成为提高合成生产率的一种重要途径。特别是IL催化的多米诺反应使得能够从简单的起始材料合成具有高区域/立体选择性的有机化合物。作为设计溶剂,IL促进的多米诺骨牌反应导致了高收率的环保绿色合成步骤。在这篇综述中,我们总结了IL催化的一锅串联反应用于合成高度官能化的有机分子。详细介绍了反应机理、区域选择性和立体选择性。本文综述了IL催化多米诺反应的合成应用。
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3.70
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