Bone tissue regeneration: biology, strategies and interface studies.

IF 4.4 3区 医学 Q2 ENGINEERING, BIOMEDICAL Progress in Biomaterials Pub Date : 2019-12-01 Epub Date: 2019-11-25 DOI:10.1007/s40204-019-00125-z
Mojtaba Ansari
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引用次数: 162

Abstract

Nowadays, bone diseases and defects as a result of trauma, cancers, infections and degenerative and inflammatory conditions are increasing. Consequently, bone repair and replacement have been developed with improvement of orthopedic technologies and biomaterials of superior properties. This review paper is intended to sum up and discuss the most relevant studies performed in the field of bone biology and bone regeneration approaches. Therefore, the bone tissue regeneration was investigated by synthetic substitutes, scaffolds incorporating active molecules, nanomedicine, cell-based products, biomimetic fibrous and nonfibrous substitutes, biomaterial-based three-dimensional (3D) cell-printing substitutes, bioactive porous polymer/inorganic composites, magnetic field and nano-scaffolds with stem cells and bone-biomaterials interface studies.

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骨组织再生:生物学、策略和界面研究。
如今,由创伤、癌症、感染以及退行性和炎症引起的骨骼疾病和缺陷正在增加。因此,随着矫形技术和性能优越的生物材料的改进,骨修复和置换得到了发展。本文旨在总结和讨论骨生物学和骨再生方法领域中最相关的研究。因此,通过合成替代品、掺入活性分子的支架、纳米药物、基于细胞的产品、仿生纤维和非纤维替代品、基于生物材料的三维(3D)细胞打印替代品、生物活性多孔聚合物/无机复合材料、,磁场和纳米支架与干细胞和骨生物材料的界面研究。
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来源期刊
Progress in Biomaterials
Progress in Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
9.60
自引率
4.10%
发文量
35
期刊介绍: Progress in Biomaterials is a multidisciplinary, English-language publication of original contributions and reviews concerning studies of the preparation, performance and evaluation of biomaterials; the chemical, physical, biological and mechanical behavior of materials both in vitro and in vivo in areas such as tissue engineering and regenerative medicine, drug delivery and implants where biomaterials play a significant role. Including all areas of: design; preparation; performance and evaluation of nano- and biomaterials in tissue engineering; drug delivery systems; regenerative medicine; implantable medical devices; interaction of cells/stem cells on biomaterials and related applications.
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