Genetic association study within the framework of Zuckerman's psychobiological personality model

IF 0.6 Q4 PSYCHOLOGY Anuario de Psicologia Pub Date : 2016-01-01 DOI:10.1016/j.anpsic.2016.06.003
Luis F. García , Anton Aluja , Oscar García , Lara Cuevas
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引用次数: 2

Abstract

Following Zuckerman's psychobiological personality model, a series of genetic association hypotheses between some polymorphisms of Serotonin, Testosterone, Dopamine, MAO-A and COMT, and three temperamental traits (Impulsive Unsocialized Sensation Seeking, Neuroticism, and Extroversion-Sociability) were tested. In order to surpass previous limitations of this kind of studies: 1) the measurement of the phenotype was improved by using eight personality scales, and 2) some statistical analyses were conducted to test conjointly the effects of the considered polymorphisms. 252 participants from two samples (147 male inmates, and 105 male healthy volunteers) were analyzed. A tendency in the theoretical expected direction is reported when several polymorphisms are considered conjointly. The discussion section recommends applying more integrative frameworks to explore the complex paths from genetics to behavior.

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祖克曼心理生物学人格模型框架下的遗传关联研究
为了突破以往这类研究的局限性:1)利用8种人格量表改进了表现型的测量;2)进行了一些统计分析,以联合检验所考虑的多态性的影响。来自两个样本的252名参与者(147名男性囚犯和105名男性健康志愿者)进行了分析。当几个多态性被联合考虑时,在理论预期方向上的趋势被报道。讨论部分建议应用更综合的框架来探索从遗传学到行为学的复杂路径。
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来源期刊
CiteScore
0.80
自引率
40.00%
发文量
21
期刊介绍: The Anuario de Psicología, one of Spain"s most important general psychology journals, is published by the Faculty of Psychology of the University of Barcelona. It appears three times a year. The Anuario combines continuity with the past with a strong commitment to the present and the future. The journal is broad-ranging, interdisciplinary, and innovative. The Anuario publishes research reports and applied studies in all fields of psychology. We also accept theorical, epistemological studies, organize dossiers on topical themes, and hold debates on controversial subjects deriving from a central article.
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